Evidence map›Paper›PMID 26178773›Full record

ArticleJournal of behavioral medicine2015

Genetic test reporting enhances understanding of risk information and acceptance of prevention recommendations compared to family history-based counseling alone.

Jennifer M Taber, Lisa G Aspinwall, Tammy K Stump, Wendy Kohlmann, Marjan Champine, Sancy A Leachman

Abstract read
In one paragraph

Article in Journal of behavioral medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Impact of personal genomic risk information on melanoma prevention behaviors and psychological outcomes: a randomized controlled trial.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Trial
  2. Review
  3. Interactive Beliefs about Genes and Behavior Predict Improved Sun Protection Following Melanoma Genetic Counseling.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022
    Article
  4. Article
  5. Article
  6. A primer in genomics for social and behavioral investigators.Translational behavioral medicine · 2020
    Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jennifer M TaberDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA.
Lisa G AspinwallDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA. lisa.aspinwall@utah.edu.
Tammy K StumpDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA.
Wendy KohlmannHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Marjan ChampineHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Sancy A LeachmanOregon Health & Science University, Portland, OR, USA.
University of Utah · USOregon Health & Science University · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
University of Utah Center for Clinical and Translational Science-UL1UL1TR000105 · NCATS · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2012 to 2013
$5.1M
Surveillance, Epidemiology and End Results (SEER) - UtahN01PC35141 · NCI · UNIVERSITY OF UTAH · PI AKERLEY I I I, WALLACE · 2007 to 2009
$4.4M
Impact of Melanoma Genetic Testing on Health Cognitions and Prevention BehaviorsR01CA158322 · NCI · UNIVERSITY OF UTAH · PI ASPINWALL, LISA G, LEACHMAN, SANCY ANN · 2011 to 2016
$2.5M
NCATS NIH HHS 8UL1TR000105NCATS NIH HHS UL1 TR000105NCI NIH HHS 5P30CA420-14NCI NIH HHS N01 PC035141NCI NIH HHS N01 PC35141NCI NIH HHS P30 CA042014NCI NIH HHS R01 CA158322NCRR NIH HHS UL1 RR025764NCRR NIH HHS UL1RR025764
6 · The paper itself

Abstract

It is unknown whether or why genetic test reporting confers benefits in the understanding and management of cancer risk beyond what patients learn from counseling based on family history. A prospective nonexperimental control group study compared participants from melanoma-prone families who underwent CDKN2A/p16 (p16) genetic testing (27 carriers, 38 noncarriers) to participants from equivalently melanoma-prone families known not to carry a deleterious p16 mutation (31 no-test controls). All participants received equivalent counseling concerning elevated lifetime melanoma risk and corresponding recommendations for prevention and screening. Both immediately and 1 month after counseling, participants receiving a genetic test result reported greater understanding of their risk, decreased derogation of the risk information, and greater personal applicability of prevention recommendations than no-test controls. Decreased derogation of risk information after test reporting predicted further increases in understanding of melanoma risk and applicability of prevention recommendations 1 month later. Results suggest unique benefits of genetic test reporting in promoting understanding and acceptance of information about hereditary cancer risk and its management.

Indexed as

Genetic CounselingGenetic Predisposition to DiseaseGenetic TestingAdolescentAdultAgedCutaneous Malignant MelanomaCyclin-Dependent Kinase Inhibitor p16FemaleHumansMaleMelanomaMiddle AgedProspective StudiesRisk FactorsSkin NeoplasmsCyclin-Dependent Kinase Inhibitor p16CDKN2A/p16Defensive processingGenetic testingIllness coherenceMelanomaUnderstanding of risk

Identifiers

PMID26178773
PMCPMC4568160
OpenAlexW1159317742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.