Evidence map›Paper›PMID 26178402›Full record

ArticleJournal of the American Heart Association2015

Impact of Fine Particulate Matter (PM2.5) Exposure During Wildfires on Cardiovascular Health Outcomes.

Anjali Haikerwal, Muhammad Akram, Anthony Del Monaco, Karen Smith, Malcolm R Sim, Mick Meyer, Andrew M Tonkin, Michael J Abramson, Martine Dennekamp

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 3 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 3 syntheses or guidelines pooled it, 243 citations in OpenAlex.

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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anjali HaikerwalDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Muhammad AkramDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Anthony Del MonacoDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Karen SmithResearch and Evaluation Department, Ambulance Victoria, Melbourne, Victoria, Australia (K.S.).
Malcolm R SimDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Mick MeyerCSIRO Oceans and Atmospheric Flagship, Aspendale, Melbourne, Victoria, Australia (M.M.).
Andrew M TonkinDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Michael J AbramsonDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Martine DennekampDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia (A.H., M.A., A.D.M., M.R.S., A.M.T., M.J.A., M.D.).
Monash University · AUAmbulance Victoria · AUCSIRO Oceans and Atmosphere · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiological studies investigating the role of fine particulate matter (PM2.5; aerodynamic diameter <2.5 μm) in triggering acute coronary events, including out-of-hospital cardiac arrests and ischemic heart disease (IHD), during wildfires have been inconclusive. METHODS AND

resultsWe examined the associations of out-of-hospital cardiac arrests, IHD, acute myocardial infarction, and angina (hospital admissions and emergency department attendance) with PM2.5 concentrations during the 2006-2007 wildfires in Victoria, Australia, using a time-stratified case-crossover study design. Health data were obtained from comprehensive health-based administrative registries for the study period (December 2006 to January 2007). Modeled and validated air exposure data from wildfire smoke emissions (daily average PM2.5, temperature, relative humidity) were also estimated for this period. There were 457 out-of-hospital cardiac arrests, 2106 emergency department visits, and 3274 hospital admissions for IHD. After adjusting for temperature and relative humidity, an increase in interquartile range of 9.04 μg/m(3) in PM2.5 over 2 days moving average (lag 0-1) was associated with a 6.98% (95% CI 1.03% to 13.29%) increase in risk of out-of-hospital cardiac arrests, with strong association shown by men (9.05%,95%CI 1.63% to 17.02%) and by older adults (aged ≥65 years) (7.25%, 95% CI 0.24% to 14.75%). Increase in risk was (2.07%, 95% CI 0.09% to 4.09%) for IHD-related emergency department attendance and (1.86%, 95% CI: 0.35% to 3.4%) for IHD-related hospital admissions at lag 2 days, with strong associations shown by women (3.21%, 95% CI 0.81% to 5.67%) and by older adults (2.41%, 95% CI 0.82% to 5.67%).

conclusionPM2.5 exposure was associated with increased risk of out-of-hospital cardiac arrests and IHD during the 2006-2007 wildfires in Victoria. This evidence indicates that PM2.5 may act as a triggering factor for acute coronary events during wildfire episodes.

Indexed as

FiresAdultAgedAge FactorsAngina PectorisCardiovascular DiseasesEmergency Service, HospitalEnvironmental ExposureFemaleHumansMaleMiddle AgedMyocardial InfarctionOut-of-Hospital Cardiac ArrestParticle SizePatient AdmissionSmokecoronary diseaseheart arrestischemic heart diseaseparticulate matterwildfires

Identifiers

PMID26178402
PMCPMC4608063
OpenAlexW2140953789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.