ArticleHuman brain mapping2015
Resting state connectivity of the bed nucleus of the stria terminalis at ultra-high field.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00047853 (fMRI Investigation of Explicit Cue and Contextual Fear), which is not on this map. Cited by 73 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
fMRI Investigation of Explicit Cue and Contextual Fear
Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Anxiety during abstinence from alcohol: A systematic review of rodent and human evidence for the anterior insula's role in the abstinence network.Addiction biology · 2021Pooled it
- Functional Subdivisions of Magnocellular Cell Groups in Human Basal Forebrain: Test-Retest Resting-State Study at Ultra-high Field, and Meta-analysis.Cerebral cortex (New York, N.Y. : 1991) · 2019Pooled it
- Age and loneliness relate to reduced trust learning and alterations in amygdala function.iScience · 2026Article
- Bed nucleus of the stria terminalis connectivity during food cue and taste processing under stress.Nature communications · 2026Article
- Remission is insufficient: predictors and mechanistic models of recurrence in late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Major depressive disorder is associated with reduced intrinsic connectivity between the bed nucleus of the stria terminalis and ventral striatum.Journal of psychiatry & neuroscience : JPN · 2026Article
- Investigating glymphatic function and bed nucleus of the stria terminalis-based functional connectivity in Parkinson's disease with and without depression.NPJ Parkinson's disease · 2025Article
- Regional hypothalamic resting state connectivity with limbic structures: An ultra-high field functional magnetic resonance imaging investigation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Fear and Anxiety in Schizophrenia: A Focus on Development, Assessment, and Mechanisms.Current topics in behavioral neurosciences · 2025Review
- The Organization of Anxiety Symptoms Along the Threat Imminence Continuum.Current topics in behavioral neurosciences · 2025Review
- Fiber architecture in the human ventromedial striatum and its relation with the bed nucleus of the stria terminalis.PloS one · 2025Article
- Bed nucleus of the stria terminalis network responses to unpredictable threat in early alcohol abstinence.Alcohol, clinical & experimental research · 2024Article
- Sex differences in neural projections of fear memory processing in mice and humans.Science advances · 2024Article
- Acute and chronic alcohol modulation of extended amygdala calcium dynamics.Alcohol (Fayetteville, N.Y.) · 2024Article
- Manual segmentation of the paraventricular nucleus of the hypothalamus and the dorsal and ventral bed nucleus of stria terminalis using multimodal 7 Tesla structural MRI: probabilistic atlases for a stress-control triad.Brain structure & function · 2024Article
- Threat Responses in Schizophrenia: A Negative Valence Systems Framework.Current psychiatry reports · 2024Review
- Exercise Modifies the Brain Metabolic Response to Chronic Cocaine Exposure Inhibiting the Stria Terminalis.Brain sciences · 2023Article
- A novel subdivision of the bed nucleus of stria terminalis in monkey, rat, and mouse brains.The Journal of comparative neurology · 2023Article
- Acute and chronic alcohol modulation of extended amygdala calcium dynamics.bioRxiv : the preprint server for biology · 2023Article
- Alterations in BNST Intrinsic Functional Connectivity in Early Abstinence from Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2023Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The bed nucleus of the stria terminalis (BNST), a portion of the "extended amygdala," is implicated in the pathophysiology of anxiety and addiction disorders. Its small size and connection to other small regions prevents standard imaging techniques from easily capturing it and its connectivity with confidence. Seed-based resting state functional connectivity is an established method for mapping functional connections across the brain from a region of interest. We, therefore, mapped the BNST resting state network with high spatial resolution using 7 Tesla fMRI, demonstrating the in vivo reproduction of many human BNST connections previously described only in animal research. We identify strong BNST functional connectivity in amygdala, hippocampus and thalamic subregions, caudate, periaqueductal gray, hypothalamus, and cortical areas such as the medial PFC and precuneus. This work, which demonstrates the power of ultra-high field for mapping functional connections in the human, is an important step toward elucidating cortical and subcortical regions and subregions of the BNST network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.