Evidence map›Paper›PMID 26178147›Full record

ArticlePediatric obesity2016

Maternal smoking in pregnancy association with childhood adiposity and blood pressure.

L Li, H Peters, A Gama, M I M Carvalhal, H G M Nogueira, V Rosado-Marques, C Padez

Open access · hybridAbstract read
In one paragraph

Article in Pediatric obesity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  11. Preterm Birth and the Type of Birth and Their Impact on the Incidence of Overweight and Obesity in Children.International journal of environmental research and public health · 2022
    Article
  12. Article
  13. Ideal cardiovascular health at age 5-6 years and cardiometabolic outcomes in preadolescence.The international journal of behavioral nutrition and physical activity · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

L LiPopulation, Policy, and Practice Programme, Institute of Child Health, University College London, London, UK.
H PetersPopulation, Policy, and Practice Programme, Institute of Child Health, University College London, London, UK.
A GamaDepartamento de Biologia Animal, Faculdade de Ciências, University of Lisbon, Lisbon, Portugal.
M I M CarvalhalUniversity of Tras-os-Montes and Alto Douro, Vila Real, Portugal.
H G M NogueiraResearch Centre for Anthropology and Health, Department of Life Sciences, University of Coimbra, Coimbra, Portugal.
V Rosado-MarquesResearch Centre for Anthropology and Health, Department of Life Sciences, University of Coimbra, Coimbra, Portugal.
C PadezResearch Centre for Anthropology and Health, Department of Life Sciences, University of Coimbra, Coimbra, Portugal.
Centre for Research in Anthropology · PTUniversity College London · GBUniversity of Lisbon · PTUniversity of Trás-os-Montes and Alto Douro · PT

Funding

Medical Research Council G0400546Medical Research Council G0601941
6 · The paper itself

Abstract

backgroundMaternal smoking during pregnancy has been associated with increased risk of childhood overweight/obesity defined by body mass index (BMI). We examined its association with a range of adiposity measures and cardiovascular indicators in children aged 3-10 years.

methodsWe used data from a cross-sectional study of schoolchildren across mainland Portuguese districts (2009-2010). We applied quantile regressions to examine maternal smoking associations with adiposity (n = 17 286), blood pressure (BP) and resting pulse rate (RPR) (n ≈ 2500) measures across the age range, adjusting for prenatal and early life factors.

resultsMaternal smoking during pregnancy was associated with increases in offspring adiposity levels. The difference in median BMI between children of smokers and non-smokers was 0.39 kg m(-2) (95% confidence interval: 0.25, 0.53) in boys and 0.46 kg m(-2) (0.31, 0.62) in girls; 0.55 cm (0.24, 0.87) and 0.82 cm (0.45, 1.19), respectively, in median waist circumference; and 0.94 mm (0.49, 1.40) and 1.47 mm (0.87, 2.07) in median sum of (triceps, subscapular, suprailiac) skin-folds. The associations appeared to be stronger with increasing age. The differences in the 90th centile tended to be greater than those in median. There was no consistent association of maternal smoking with BP and RPR.

conclusionsChildren whose mother smoked during pregnancy had higher adiposity levels than children of non-smokers, across several measures, particularly among older children. Although there was no consistent association with cardiovascular indicators, maternal smoking association with childhood obesity may have implications for cardiovascular risk factors over the life course.

Indexed as

Blood PressurePrenatal Exposure Delayed EffectsAdiposityBody Mass IndexCardiovascular DiseasesChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMothersOverweightPediatric ObesityPregnancyRisk FactorsAdiposityblood pressurechildrenmaternal smoking in pregnancy

Identifiers

PMID26178147
PMCPMC4949567
OpenAlexW1940858464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.