ArticleHuman brain mapping2015
The subthalamic nucleus during decision-making with multiple alternatives.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Subthalamic stimulation causally modulates human voluntary decision-making to stay or go.NPJ Parkinson's disease · 2024Article
- Probabilistic causal reasoning under time pressure.PloS one · 2024Article
- Degenerate boundaries for multiple-alternative decisions.Nature communications · 2022Article
- Conflict Detection in a Sequential Decision Task Is Associated with Increased Cortico-Subthalamic Coherence and Prolonged Subthalamic Oscillatory Response in the β Band.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Characterizing the role of the pre-SMA in the control of speed/accuracy trade-off with directed functional connectivity mapping and multiple solution reduction.Human brain mapping · 2019Article
- Having More Choices Changes How Human Observers Weight Stable Sensory Evidence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Event-related deep brain stimulation of the subthalamic nucleus affects conflict processing.Annals of neurology · 2018Article
- Visualizing the Human Subcortex Using Ultra-high Field Magnetic Resonance Imaging.Brain topography · 2018Review
- The Connectivity Fingerprint of the Human Frontal Cortex, Subthalamic Nucleus, and Striatum.Frontiers in neuroanatomy · 2018Article
- Comparing functional MRI protocols for small, iron-rich basal ganglia nuclei such as the subthalamic nucleus at 7 T and 3 T.Human brain mapping · 2017Article
- Meta-Analysis of the Relationship between Deep Brain Stimulation in Patients with Parkinson's Disease and Performance in Evaluation Tests for Executive Brain Functions.Parkinson's disease · 2017Review
- Towards a mechanistic understanding of the human subcortex.Nature reviews. Neuroscience · 2016Review
- Stop-related subthalamic beta activity indexes global motor suppression in Parkinson's disease.Movement disorders : official journal of the Movement Disorder Society · 2016Article
- Uses, misuses, new uses and fundamental limitations of magnetic resonance imaging in cognitive science.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Tuning the Brake While Raising the Stake: Network Dynamics during Sequential Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- ERP Correlates of Simulated Purchase Decisions.Frontiers in neuroscience · 2016Article
- Believer-Skeptic Meets Actor-Critic: Rethinking the Role of Basal Ganglia Pathways during Decision-Making and Reinforcement Learning.Frontiers in neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Several prominent neurocomputational models predict that an increase of choice alternatives is modulated by increased activity in the subthalamic nucleus (STN). In turn, increased STN activity allows prolonged accumulation of information. At the same time, areas in the medial frontal cortex such as the anterior cingulate cortex (ACC) and the pre-SMA are hypothesized to influence the information processing in the STN. This study set out to test concrete predictions of STN activity in multiple-alternative decision-making using a multimodal combination of 7 Tesla structural and functional Magnetic Resonance Imaging, and ancestral graph (AG) modeling. The results are in line with the predictions in that increased STN activity was found with an increasing amount of choice alternatives. In addition, our study shows that activity in the ACC is correlated with activity in the STN without directly modulating it. This result sheds new light on the information processing streams between medial frontal cortex and the basal ganglia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.