Evidence map›Paper›PMID 26178026›Full record

SynthesisAdvances in nutrition (Bethesda, Md.)2015

Maternal micronutrient deficiencies and related adverse neonatal outcomes after bariatric surgery: a systematic review.

Goele Jans, Christophe Matthys, Annick Bogaerts, Matthias Lannoo, Johan Verhaeghe, Bart Van der Schueren, Roland Devlieger

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Advances in nutrition (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Breastfeeding in metabolic and bariatric patients: a comprehensive guide for surgeons, patients, and the multidisciplinary team.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025
    Review
  8. Review
  9. Article
  10. Advances in Perioperative Nutritional Management in Metabolic and Bariatric Surgery.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Goele JansDepartments of Development and Regeneration and.
Christophe MatthysClinical and Experimental Medicine, KU Leuven, Leuven, Belgium; Departments of Endocrinology.
Annick BogaertsUniversity College Leuven, Hasselt, Belgium; Center for Research and Innovation in Care, Department of Nursing and Midwifery Sciences, University of Antwerp, Antwerp, Belgium; and.
Matthias LannooClinical and Experimental Medicine, KU Leuven, Leuven, Belgium; Abdominal Surgery, and.
Johan VerhaegheDepartments of Development and Regeneration and Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium;
Bart Van der SchuerenClinical and Experimental Medicine, KU Leuven, Leuven, Belgium; Departments of Endocrinology.
Roland DevliegerDepartments of Development and Regeneration and Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium; Department of Obstetrics, Gynecology, and Reproduction, GZA, Wilrijk, Belgium roland.devlieger@uzleuven.be.
KU Leuven · BEGZA Ziekenhuizen Campus Sint-Augustinus · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnant and postpartum women with a history of bariatric surgery are at risk of micronutrient deficiencies as a result of the combination of physiologic changes related to pregnancy and iatrogenic postoperative alterations in the absorption and metabolism of crucial nutrients. This systematic review investigates micronutrient deficiencies and related adverse clinical outcomes in pregnant and postpartum women after bariatric surgery. A systematic approach involving critical appraisal was conducted independently by 2 researchers to examine deficiencies of phylloquinone, folate, iron, calcium, zinc, magnesium, iodide, copper, and vitamins A, D, and B-12 in pregnant and postpartum women after bariatric surgery, together with subsequent outcomes in the neonates. The search identified 29 relevant cases and 8 cohort studies. The quality of reporting among the case reports was weak according to the criteria based on the CARE (CAse REporting) guidelines as was that for the cohort studies based on the criteria from the Cohort Study Quality Assessment list of the Dutch Cochrane Center. The most common adverse neonatal outcomes related to maternal micronutrient deficiencies include visual complications (vitamin A), intracranial hemorrhage (phylloquinone), neurological and developmental impairment (vitamin B-12), and neural tube defects (folate). On the basis of the systematically collected information, we conclude that the evidence on micronutrient deficiencies in pregnant and postpartum women after bariatric surgery and subsequent adverse neonatal outcomes remains weak and inconclusive.

Indexed as

Pregnancy ComplicationsPregnancy OutcomeBariatric SurgeryCohort StudiesFemaleFolic Acid DeficiencyHumansInfant, NewbornInfant, Newborn, DiseasesIntracranial HemorrhagesMicronutrientsNeural Tube DefectsPregnancyVision DisordersVitamin A DeficiencyVitamin B 12 DeficiencyMicronutrientsbariatric surgeryearly postpartumgestationmaternal nutritionmicronutrientsneonatal complicationsobesity surgerypregnancy

Identifiers

PMID26178026
PMCPMC4496736
OpenAlexW1736439977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.