ArticleJournal of molecular evolution2015
Evolution of Eukaryotic DNA Polymerases via Interaction Between Cells and Large DNA Viruses.
Article in Journal of molecular evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Local microenvironments of capsomer variants in the PBCV-1.Journal of structural biology · 2025Article
- Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses.Nature communications · 2025Article
- Ancient Host-Virus Gene Transfer Hints at a Diverse Pre-LECA Virosphere.Journal of molecular evolution · 2025Article
- Evolution of ubiquitin, cytoskeleton, and vesicular trafficking machinery in giant viruses.Journal of virology · 2025Article
- Co-infection of phylogenetically distinct nucleocytoviruses in Acanthamoeba castellanii cells.FEMS microbiology letters · 2025Article
- Evolutionary Dynamics of Accelerated Antiviral Resistance Development in Hypermutator Herpesvirus.Molecular biology and evolution · 2024Article
- Virologs, viral mimicry, and virocell metabolism: the expanding scale of cellular functions encoded in the complex genomes of giant viruses.FEMS microbiology reviews · 2023Article
- Viral histones: pickpocket's prize or primordial progenitor?Epigenetics & chromatin · 2022Review
- Giant Viruses Encode Actin-Related Proteins.Molecular biology and evolution · 2022Article
- Coevolutionary and Phylogenetic Analysis of Mimiviral Replication Machinery Suggest the Cellular Origin of Mimiviruses.Molecular biology and evolution · 2021Article
- Medusavirus Ancestor in a Proto-Eukaryotic Cell: Updating the Hypothesis for the Viral Origin of the Nucleus.Frontiers in microbiology · 2020Article
- Diversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Medusavirus, a Novel Large DNA Virus Discovered from Hot Spring Water.Journal of virology · 2019Article
- Fifteen Marseilleviruses Newly Isolated From Three Water Samples in Japan Reveal Local Diversity ofFrontiers in microbiology · 2019Article
- Taxon Richness of "Megaviridae" Exceeds those of Bacteria and Archaea in the Ocean.Microbes and environments · 2018Article
- Novel Abundant Oceanic Viruses of Uncultured Marine Group II Euryarchaeota.Current biology : CB · 2017Article
- A Glimpse of Nucleo-Cytoplasmic Large DNA Virus Biodiversity through the Eukaryotic Genomics Window.Viruses · 2017Article
- Morphological and Taxonomic Properties of Tokyovirus, the First Marseilleviridae Member Isolated from Japan.Microbes and environments · 2016Article
- Review
- Complete Genome Sequence of a New Megavirus Family Member Isolated from an Inland Water Lake for the First Time in India.Genome announcements · 2016Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
B-family DNA-directed DNA polymerases are DNA replication enzymes found in Eukaryota, Archaea, large DNA viruses, and in some, but not all, bacteria. Several polymerase domains are conserved among the B-family DNA polymerases from these organisms, suggesting that the B-family DNA polymerases evolved from a common ancestor. Eukaryotes retain at least three replicative B-family DNA polymerases, DNA polymerase α, δ, and ε, and one translesion B-family DNA polymerase, DNA polymerase ζ. Here, we present molecular evolutionary evidence that suggests DNA polymerase genes evolved through horizontal gene transfer between the viral and archaeal-eukaryotic lineages. Molecular phylogenetic analyses of the B-family DNA polymerases from nucleo-cytoplasmic large DNA viruses (NCLDVs), eukaryotes, and archaea suggest that different NCLDV lineages such as Poxviridae and Mimiviridae were involved in the evolution of different DNA polymerases (pol-α-, δ-, ε-, and ζ-like genes) in archaeal-eukaryotic cell lineages, putatively through horizontal gene transfer. These results support existing theories that link the evolution of NCLDVs and the origin of the eukaryotic nucleus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.