Evidence map›Paper›PMID 26177801›Full record

ArticleEuropean journal of epidemiology2016

Placental abruption and long-term maternal cardiovascular disease mortality: a population-based registry study in Norway and Sweden.

Lisa DeRoo, Rolv Skjærven, Allen Wilcox, Kari Klungsøyr, Anna-Karin Wikström, Nils-Halvdan Morken, Sven Cnattingius

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Disparities in Cardiovascular Disease in Women with Adverse Pregnancy Outcomes.medRxiv : the preprint server for health sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Lisa DeRooDepartment of Global Public Health and Primary Health Care, University of Bergen, Postboks 7804, 5018, Bergen, Norway. Lisa.De.Roo@igs.uib.no.
Rolv SkjærvenDepartment of Global Public Health and Primary Health Care, University of Bergen, Postboks 7804, 5018, Bergen, Norway.
Allen WilcoxNational Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Kari KlungsøyrDepartment of Global Public Health and Primary Health Care, University of Bergen, Postboks 7804, 5018, Bergen, Norway.
Anna-Karin WikströmDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Nils-Halvdan MorkenDepartment of Global Public Health and Primary Health Care, University of Bergen, Postboks 7804, 5018, Bergen, Norway.
Sven CnattingiusClinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden.
University of Bergen · NOKarolinska Institutet · SENational Institute of Environmental Health Sciences · USNorwegian Institute of Public Health · NO

Funding

Epidemiologic Study Of Reproductive Outcomes And Environmental ExposuresZIAES044003 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WILCOX, ALLEN J · 2009 to 2020
$4.7M
6 · The paper itself

Abstract

Women with preeclamptic pregnancies have increased long-term cardiovascular disease (CVD) mortality. We explored this mortality risk among women with placental abruption, another placental pathology. We used linked Medical Birth Registry and Death Registry data to study CVD mortality among over two million women with a first singleton birth between 1967 and 2002 in Norway and 1973 and 2003 in Sweden. Women were followed through 2009 and 2010, respectively, to ascertain subsequent pregnancies and mortality. Cox regression analysis was used to estimate associations between placental abruption and cardiovascular mortality adjusting for maternal age, education, year of the pregnancy and country. There were 49,944 deaths after an average follow-up of 23 years, of which 5453 were due to CVD. Women with placental abruption in first pregnancy (n = 10,981) had an increased risk of CVD death (hazard ratio 1.8; 95 % confidence interval 1.3, 2.4). Results were essentially unchanged by excluding women with pregestational hypertension, preeclampsia or diabetes. Women with placental abruption in any pregnancy (n = 23,529) also had a 1.8-fold increased risk of CVD mortality (95 % confidence interval 1.5, 2.2) compared with women who never experienced the condition. Our findings provide evidence that placental abruption, like other placental complications of pregnancy, is associated with women's increased risk of later CVD mortality.

Indexed as

Abruptio PlacentaeAdultCardiovascular DiseasesFemaleFollow-Up StudiesHumansHypertensionHypertension, Pregnancy-InducedLongitudinal StudiesMaternal AgeNetherlandsNorwayPopulation SurveillancePre-EclampsiaPregnancyPregnancy Complications, CardiovascularCardiovascular diseaseMortalityPlacental abruptionWomen

Identifiers

PMID26177801
PMCPMC4901083
OpenAlexW2139506236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.