ArticleDigestive diseases and sciences2015
Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding.
Article in Digestive diseases and sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Changing Epidemiology and Etiology of Upper Gastrointestinal Bleeding.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- Impact of Urgent Versus Early Endoscopy on Outcomes in Acute Upper Gastrointestinal Bleeding: A Retrospective Study.Canadian journal of gastroenterology & hepatology · 2025Article
- Cricothyrotomy in Acute Upper Gastrointestinal Bleed: A Difficult Airway Simulation Case for Anesthesiology Residents.MedEdPORTAL : the journal of teaching and learning resources · 2024Article
- Myocardial injury is a risk factor for 6-week mortality in liver cirrhosis associated esophagogastric variceal bleeding.Scientific reports · 2023Article
- Prevention of the Pro-Aggressive Effects of Ethanol-Intoxicated Mice by Schisandrin B.Nutrients · 2023Article
- Retrospective analysis of risk factors for non-variceal upper gastrointestinal bleeding and construction of a nomogram prediction model.American journal of translational research · 2023Article
- Article
- Gastric Ulcer Healing Property ofFrontiers in pharmacology · 2021Article
- Effects of alcohol on c-Myc protein in the brain.Behavioural brain research · 2017Article
- Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis.World journal of gastroenterology · 2016Article
- A Prospective Study of Alcohol Consumption and Smoking and the Risk of Major Gastrointestinal Bleeding in Men.PloS one · 2016Article
- Extrahepatic Manifestations in Alcoholic Liver Disease.Journal of clinical and experimental hepatologyReview
- Risk factors of in-hospital mortality among patients with upper gastrointestinal bleeding and acute myocardial infarction.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo current data are available on rebleeding and mortality risk in patients who use alcohol excessively and are admitted for non-variceal upper gastrointestinal bleeding (NVUGIB). This information could help in planning interventions and follow-up protocols for these patients.
aimThis study provides contemporary data on the long-term outcome after first-time NVUGIB in alcohol abusers (AAs) compared to non-abusers (NAs).
methodsConsecutive patients hospitalized for their first acute gastrointestinal bleeding from 2009 through 2011 were retrospectively recorded and categorized as AA or NA. Risk factors for one-year mortality and rebleeding were identified, and patients were further monitored for long-term mortality until 2015.
resultsAlcohol abuse was identified in 19.7% of patients with NVUGIB (n = 518). The one-year rebleeding rate was 16.7% in AAs versus 9.1% in NAs (P = 0.027). Alcohol abuse was associated with a twofold increase in rebleeding risk (P = 0.025); the risk especially increased 6 months after the initial bleeding. The study groups did not differ significantly in 30-day (6.0%) or one-year mortality rates (20.5%). However, there was a tendency for higher overall mortality in AAs than NAs after adjustment of comorbidities.
conclusionAAs with NVUGIB are at high risk of rebleeding, and mortality is increased in AA patients. A close follow-up strategy and long-term proton pump inhibitor therapy are recommended for AA patients with peptic ulcer or esophagitis.
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