ArticleEarly intervention in psychiatry2017
Domain-specific impairment in cognitive control among remitted youth with a history of major depression.
Article in Early intervention in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Neurocognitive deficits in depression: a systematic review of cognitive impairment in the acute and remitted state.European archives of psychiatry and clinical neuroscience · 2023Pooled it
- Cognitive impairment and associated factors among patients with mood disorders receiving care at public hospitals in Gedeo zone, Southern Ethiopia.Social psychiatry and psychiatric epidemiology · 2026Article
- Early Emergence of Rumination has no Association with Performance on a Non-affective Inhibitory Control Task.Child psychiatry and human development · 2024Article
- Change on the Repeatable Battery for the Assessment of Neuropsychological Status and its relationship to brain amyloid.Journal of clinical and experimental neuropsychology · 2023Article
- Relations of gray matter volume to dimensional measures of cognition and affect in mood disorders.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Article
- Current Evidence and Theories in Understanding the Relationship between Cognition and Depression in Childhood and Adolescence: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- The Quick Dementia Rating System and Its Relationship to Biomarkers of Alzheimer's Disease and Neuropsychological Performance.Dementia and geriatric cognitive disorders · 2022Article
- Cognitive Impairment and Neurocognitive Profiles in Major Depression-A Clinical Perspective.Frontiers in psychiatry · 2022Review
- Set Shifting and Inhibition Deficits as Potential Endophenotypes for Depression.Psychiatry research · 2021Article
- The MATRICS Consensus Cognitive Battery: Psychometric Properties of the Chinese Version in Young Patients With Major Depression Disorder.Frontiers in psychiatry · 2021Article
- Disentangling vulnerability, state and trait features of neurocognitive impairments in depression.Brain : a journal of neurology · 2020Article
- A Lifespan Model of Interference Resolution and Inhibitory Control: Risk for Depression and Changes with Illness Progression.Neuropsychology review · 2020Review
- Is cognitive dysfunction involved in difficult-to-treat depression? Characterizing resistance from a cognitive perspective.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
- Questioning the Effort Hypothesis That Depressed Patients Perform Disproportionately Worse on Effortful Cognitive Tasks.Perceptual and motor skills · 2020Article
- A Longitudinal 5-Year Follow-Up Study of Cognitive Function After First Episode Major Depressive Disorder: Exploring State, Scar and Trait Effects.Frontiers in psychiatry · 2020Article
- Magnitude and correlates of cognitive impairment among major depressive disorder patients in Addis Ababa: institution based cross-sectional study.BMC research notes · 2019Article
- Cognitive Control as a 5-HTFrontiers in psychology · 2019Article
- Differential engagement of cognitive control regions and subgenual cingulate based upon presence or absence of comorbid anxiety with depression.Journal of affective disorders · 2018Article
- Predictors of Attrition in Longitudinal Neuroimaging Research: Inhibitory Control, Head Movement, and Resting-State Functional Connectivity.Brain connectivity · 2018Article
- Cognitive control and network disruption in remitted depression: a correlate of childhood adversity.Social cognitive and affective neuroscience · 2018Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
aimImpairment in neuropsychological functioning is common in major depressive disorder (MDD), but it is not clear to what degree these deficits are related to risk (e.g. trait), scar, burden or state effects of MDD. The objective of this study was to use neuropsychological measures, with factor scores in verbal fluency, processing speed, attention, set-shifting and cognitive control in a unique population of young, remitted, unmedicated, early course individuals with a history of MDD in hopes of identifying putative trait markers of MDD.
methodsYouth aged 18-23 in remission from MDD (rMDD; n = 62) and healthy controls (HC; n = 43) were assessed with neuropsychological tests at two time points. These were from four domains of executive functioning, consistent with previous literature as impaired in MDD: verbal fluency and processing speed, conceptual reasoning and set-shifting, processing speed with interference resolution, and cognitive control.
resultsrMDD youth performed comparably to HCs on verbal fluency and processing speed, processing speed with interference resolution, and conceptual reasoning and set-shifting, reliably over time. Individuals with rMDD demonstrated relative decrements in cognitive control at Time 1, with greater stability than HC participants.
conclusionMDD may be characterized by regulatory difficulties that do not pertain specifically to active mood state or fluctuations in symptoms. Deficient cognitive control may represent a trait vulnerability or early course scar of MDD that may prove a viable target for secondary prevention or early remediation.
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