Evidence map›Paper›PMID 26177484›Full record

ReviewThe review of diabetic studies : RDS

Alternative Medicine in Diabetes - Role of Angiogenesis, Oxidative Stress, and Chronic Inflammation.

Mohamed F El-Refaei, Suha H Abduljawad, Ahmed H Alghamdi

Open access · bronzeAbstract readReview
In one paragraph

Review in The review of diabetic studies : RDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Oxidative Stress and the Kidney in the Space Environment.International journal of molecular sciences · 2018
    Review
  8. Article
  9. Article
  10. Ergosterol Alleviates Kidney Injury in Streptozotocin-Induced Diabetic Mice.Evidence-based complementary and alternative medicine : eCAM · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Mohamed F El-RefaeiGenetic Engineering and Biotechnology Institute, Sadat City University, Egypt.
Suha H AbduljawadFaculty of Family Science, Taibah University, Kingdom of Saudi Arabia.
Ahmed H AlghamdiFaculty of Medicine, Albaha University, Kingdom of Saudi Arabia.
Al Baha University · SATaibah University · SAUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is a chronic metabolic disorder that is characterized by hyperglycemia due to lack of or resistance to insulin. Patients with diabetes are frequently afflicted with ischemic vascular disease and impaired wound healing. Type 2 diabetes is known to accelerate atherosclerotic processes, endothelial cell dysfunction, glycosylation of extracellular matrix proteins, and vascular denervation. Herbal medicines and naturally occurring substances may positively affect diabetes management, and could thus be utilized as cost-effective means of supporting treatment in developing countries. Natural treatments have been used in these countries for a long time to treat diabetes. The present review analyses the features of aberrant angiogenesis, abnormalities in growth factors, oxidative stress, and metabolic derangements relevant to diabetes, and how herbal substances and their active chemical constituents may counteract these events. Evidence for possible biochemical effectiveness and limitations of herbal medicines are given, as well as details regarding the role of cytokines and nitric oxide.

Indexed as

Complementary TherapiesNeovascularization, PhysiologicOxidative StressAngiogenesis InhibitorsChronic DiseaseDiabetes Mellitus, Type 2HumansHypoglycemic AgentsInflammationPlant PreparationsVascular Endothelial Growth Factor AAngiogenesis InhibitorsHypoglycemic AgentsPlant PreparationsVascular Endothelial Growth Factor A

Identifiers

PMID26177484
PMCPMC5397289
OpenAlexW1003335003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.