ArticleInternational journal of surgery case reports2015
Duodenal metastasis from lung adenocarcinoma: A rare cause of melena.
Article in International journal of surgery case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 22 citations in OpenAlex.
- Durable response to immunotherapy in NSCLC with duodenal metastasis.Discover oncology · 2026Article
- Duodenal metastasis from primary lung adenocarcinoma: A rare case report.Radiology case reports · 2024Article
- Symptomatic duodenal metastasis from a small cell lung cancer primary: a rare case.Frontline gastroenterology · 2024Article
- Delayed Diagnosis of Duodenal Metastasis From Primary Lung Adenocarcinoma: A Case Report.Cureus · 2023Article
- Lung carcinoma with small intestinal metastases and gastrointestinal bleeding: A rare case report.Oncology letters · 2023Article
- Upper gastrointestinal haemorrhage caused by duodenal metastasis from primary lung cancer: A case report.Respirology case reports · 2023Article
- EUS-guided fine needle aspiration provides an open view for duodenal obstruction caused by urothelial carcinoma: a case report.BMC gastroenterology · 2022Article
- Gastrointestinal hemorrhage caused by duodenal metastasis from a primary lung adenocarcinoma: A case report.Molecular and clinical oncology · 2021Article
- Upper Gastrointestinal Bleed due to Duodenal Metastases of Lung Adenocarcinoma: Report of Two Cases and Review of Literature.Case reports in medicine · 2019Article
- A Rare Case of Ureteral Carcinoma with Recurrence in the Duodenum Requiring Double Stenting.Internal medicine (Tokyo, Japan) · 2017Article
- Article
- Duodenal Metastases from Lung Carcinoma.Internal medicine (Tokyo, Japan) · 2017Article
- A Rare Presentation of Poorly Differentiated Lung Carcinoma with Duodenal Metastasis and Literature Review.Case reports in gastroenterologyArticle
- Rare Case of Duodenal Metastasis From Pulmonary Squamous Cell Carcinoma.Journal of investigative medicine high impact case reportsArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionWe report a rare case of duodenal metastasis from primary lung adenocarcinoma presented with history of melena and weight loss. PRESENTATION OF CASE: A 52-year-old smoker man presented with six months history of epigastric pain, melena and weight loss. Esophago-gastroduodenoscopy revealed a 10mm ulcerative lesion in the fourth part of duodenum. Histopathology of resected lesion showed poorly differentiated adenocarcinoma. Tumor cells showed immunopositivity for cytokeratin-7 (CK7), thyroid transcription factor 1 (TTF-1), and immunonegativity for CK20, Villin, CDX2 and thyroglobulin, supporting the diagnosis of metastatic adenocarcinoma of the lung origin. Computed tomography (CT) of chest revealed left hilar mass encasing the main pulmonary artery associated with ipsilateral hilar and contralateral mediastinal lymphadenopathy. Bronchoscopy assisted biopsy of lung mass confirmed the diagnosis of primary adenocarcinoma. Patient was staged as T4N3M1. After the resection of duodenal metastasis followed by three cycles of cisplatinum based chemotherapy with Bevacizumab, melena resolved completely. DISCUSSION: Duodenal metastases from lung adenocarcinoma are extremely uncommon, and rarely produce symptoms. Most of cases require duodenectomy or pancreatico-duodenectomy for symptomatic relief. For smaller duodenal metastatic lesions (≤1cm) endoscopic resection is a feasible therapeutic option.
conclusionAlthough rare, duodenal metastasis from lung adenocarcinoma should also be included in the differential diagnosis of melena. Smaller lesions (≤1cm) can safely be managed with endoscopic resection.
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