ReviewJournal of natural products2015
Countercurrent Separation of Natural Products: An Update.
Review in Journal of natural products, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 287 citations in OpenAlex.
- Multilevel Residual Complexity Analysis Reveals Origin of Nanomolar Antiviral Bioactives of "Isoquercitrin".Journal of natural products · 2026Article
- A deep dive into herbal extraction: Techniques, trends, and technological advancements.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2026Article
- Integrated counter current separation and omics approaches for discovery of bioactive compounds from medicinal plants.Frontiers in pharmacology · 2026Review
- Development of a Novel Rotor Design for Counter-Current Centrifugal Extraction Based on Computational Fluid Dynamics Simulations.Journal of separation science · 2025Article
- Continuous Liquid-Liquid Extraction of High-Purity Lutein fromFoods (Basel, Switzerland) · 2025Article
- Centrifugal Partition Chromatography Is a Powerful Tool for the Isolation of Antibiofilm Quantum Carbon Dots Synthesized by Hydrothermal Treatment of Avocado Peels.Molecules (Basel, Switzerland) · 2025Article
- Natural Product-Derived Senotherapeutics: Extraction and Biological Evaluation Techniques.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.Planta medica · 2024Article
- Countercurrent chromatography separation of vitamin E isomers in a co-current mode.Journal of separation science · 2023Article
- Coumarins from Jinhua Finger Citron: Separation by Liquid-Liquid Chromatography and Potential Antitumor Activity.Molecules (Basel, Switzerland) · 2023Article
- Enrichment and structural assignment of geometric isomers of unsaturated furan fatty acids.Analytical and bioanalytical chemistry · 2023Article
- Sample preparation of free sterols from vegetable oils by countercurrent chromatography in co-current mode.Analytical and bioanalytical chemistry · 2023Article
- Effective isolation of cannabidiol and cannabidiolic acid free of psychotropic phytocannabinoids from hemp extract by fast centrifugal partition chromatography.Analytical and bioanalytical chemistry · 2023Article
- Profiling and Isolation of Ten Rare Branched-Chain Alkylresorcinols in Quinoa.Molecules (Basel, Switzerland) · 2023Article
- B-type Proanthocyanidins with Dentin Biomodification Activity from Cocoa (Journal of agricultural and food chemistry · 2022Article
- Isoquinoline Alkaloids fromInternational journal of molecular sciences · 2022Article
- Online hyphenation of centrifugal partition chromatography with countercurrent chromatography (CPC-CCC) and its application to the separation of saturated alkylresorcinols.Analytical and bioanalytical chemistry · 2022Article
- Anthocyanins: Traditional Uses, Structural and Functional Variations, Approaches to Increase Yields and Products' Quality, Hepatoprotection, Liver Longevity, and Commercial Products.International journal of molecular sciences · 2022Review
- Efficient Isolation of Mycosporine-Like Amino Acids from Marine Red Algae by Fast Centrifugal Partition Chromatography.Marine drugs · 2022Article
- Alternative Extraction and Downstream Purification Processes for Anthocyanins.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
This work assesses the current instrumentation, method development, and applications in countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC), collectively referred to as countercurrent separation (CCS). The article provides a critical review of the CCS literature from 2007 since our last review (J. Nat. Prod. 2008, 71, 1489-1508), with a special emphasis on the applications of CCS in natural products research. The current state of CCS is reviewed in regard to three continuing topics (instrumentation, solvent system development, theory) and three new topics (optimization of parameters, workflow, bioactivity applications). The goals of this review are to deliver the necessary background with references for an up-to-date perspective of CCS, to point out its potential for the natural product scientist, and thereby to induce new applications in natural product chemistry, metabolome, and drug discovery research involving organisms from terrestrial and marine sources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.