ArticlePloS one2015
Erectile Dysfunction in Patients with Sleep Apnea--A Nationwide Population-Based Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Association between obstructive sleep apnea and erectile dysfunction: a systematic review and meta-analysis.International journal of impotence research · 2018Pooled it
- Association between obstructive sleep apnea and male sexual dysfunction: a prospective cohort study based on 155,688 participants from the UK Biobank.Scientific reports · 2026Article
- Causal relationship between sleep traits and erectile dysfunction: evidence from Mendelian randomization analysis.Archives of medical science : AMS · 2025Article
- Investigating self-reported efficacy of lifestyle medicine approaches to tackle erectile dysfunction: a cross-sectional eSurvey based study.BMC urology · 2023Article
- Poor sleep quality and erectile dysfunction in students from a Peruvian University: A cross-sectional study.Frontiers in public health · 2023Article
- The relationship between obstructive sleep apnoea and erectile dysfunction: An underdiagnosed link? A prospective cross-sectional study.Andrologia · 2022Article
- Risk of Ocular Adverse Events Associated With Use of Phosphodiesterase 5 Inhibitors in Men in the US.JAMA ophthalmology · 2022Article
- The association between cataract and sleep apnea: a nationwide population-based cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Erectile Dysfunction and Obstructive Sleep Apnea: A Review.Frontiers in psychiatry · 2022Review
- Risk of pneumothorax in pneumoconiosis patients in Taiwan: a retrospective cohort study.BMJ open · 2021Article
- Obstructive sleep apnea syndrome as a potential cause of sexual dysfunction in women : Sexual dysfunction in women.Sleep & breathing = Schlaf & Atmung · 2021Article
- Ocular Complications of Obstructive Sleep Apnea.Journal of clinical medicine · 2021Review
- Increased risk of major depressive disorder in sleep apnea patients in Taiwan.Scientific reports · 2021Article
- The Association between Temporomandibular Disorder and Sleep Apnea-A Nationwide Population-Based Cohort Study.International journal of environmental research and public health · 2020Article
- Blood Oxygen Accumulation Distribution Area Index Is Associated With Erectile Dysfunction in Patients With Sleep Apnea-Results From a Cross-sectional Study.Sexual medicine · 2020Article
- May Dyspnea Sensation Influence the Sexual Function in Men With Obstructive Sleep Apnea Syndrome? A Prospective Control Study.Sexual medicine · 2019Article
- CHADS₂, CHA₂DS₂ASc, and New ABCD Scores Predict the Risk of Peripheral Arterial Disease in Patients with Sleep Apnea.Journal of clinical medicine · 2019Article
- Association Between Erectile Dysfunction and Subsequent Prostate Cancer Development: A Population-Based Cohort Study With Double Concurrent Comparison Groups.American journal of men's health · 2018Article
- The uses of overnight pulse oximetry.Lung India : official organ of Indian Chest SocietyReview
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased incidence of erectile dysfunction (ED) has been reported among patients with sleep apnea (SA). However, this association has not been confirmed in a large-scale study. We therefore performed a population-based cohort study using Taiwan National Health Insurance (NHI) database to investigate the association of SA and ED. From the database of one million representative subjects randomly sampled from individuals enrolled in the NHI system in 2010, we identified adult patients having SA and excluded those having a diagnosis of ED prior to SA. From these suspected SA patients, those having SA diagnosis after polysomnography were defined as probable SA patients. The dates of their first SA diagnosis were defined as their index dates. Each SA patient was matched to 30 randomly-selected, age-matched control subjects without any SA diagnosis. The control subjects were assigned index dates as their corresponding SA patients, and were ensured having no ED diagnosis prior to their index dates. Totally, 4,835 male patients with suspected SA (including 1,946 probable SA patients) were matched to 145,050 control subjects (including 58,380 subjects matched to probable SA patients). The incidence rate of ED was significantly higher in probable SA patients as compared with the corresponding control subjects (5.7 vs. 2.3 per 1000 patient-year; adjusted incidence rate ratio = 2.0 [95% CI: 1.8-2.2], p<0.0001). The cumulative incidence was also significantly higher in the probable SA patients (p<0.0001). In multivariable Cox regression analysis, probable SA remained a significant risk factor for the development of ED after adjusting for age, residency, income level and comorbidities (hazard ratio = 2.0 [95%CI: 1.5-2.7], p<0.0001). In line with previous studies, this population-based large-scale study confirmed an increased ED incidence in SA patients in Chinese population. Physicians need to pay attention to the possible underlying SA while treating ED patients.
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