ArticleMolecular plant pathology2016
Identification of I-7 expands the repertoire of genes for resistance to Fusarium wilt in tomato to three resistance gene classes.
Article in Molecular plant pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 115 citations in OpenAlex.
- The Conserved Guanyl-Specific Ribonuclease T1 Effector EC19 Is Required for Full Virulence of the Vascular Wilt Fungus Fusarium oxysporum on Tomato.Molecular plant pathology · 2026Article
- Solanaceous vegetables andHorticulture research · 2026Article
- Current Understanding of Cell-Surface Immune Receptors for MAMPs and Plant Parasites in the Solanaceae Family.Molecular plant pathology · 2026Review
- Intraspecific Grafting of Tomatoes: Impact of Disease-Resistant Rootstocks on Fusarium Wilt Prevention, Plant Growth, and Fruit Quality under Naturally Infested Field Conditions.The plant pathology journal · 2025Article
- A well-annotated genome of Apium graveolens var. dulce cv. Challenger, a celery with resistance to Fusarium oxysporum f. sp. apii race 2.The Plant journal : for cell and molecular biology · 2025Article
- Molecular breeding of tomato: Advances and challenges.Journal of integrative plant biology · 2025Review
- Map-Based Cloning and Characterization of a Major QTL Gene,International journal of molecular sciences · 2024Article
- In silico identification of a promising inhibitor of Fusarium oxysporum f. sp. Lycopersici, Secreted in Xylem 1 protein.Molecular diversity · 2024Article
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- The structural repertoire ofeLife · 2024Article
- Fine-mapping of a major locus for Fusarium wilt resistance in flax (Linum usitatissimum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- TomatoFrontiers in plant science · 2024Article
- Vegetable biology and breeding in the genomics era.Science China. Life sciences · 2023Review
- Mutation introduced in DDTFR10/A gene of ethylene response element-binding protein (EREBP) family through CRISPR/Cas9 genome editing confers increased Fusarium wilt tolerance in tomato.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Transcriptome Analysis of Fusarium-Tomato Interaction Based on an Updated Genome Annotation ofJournal of fungi (Basel, Switzerland) · 2022Article
- Novel Fusarium wilt resistance genes uncovered in natural and cultivated strawberry populations are found on three non-homoeologous chromosomes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Genome-Wide Analysis of theGenes · 2022Article
- An autopolyploid-suitable polyBSA-seq strategy for screening candidate genetic markers linked to leaf blight resistance in sugarcane.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Defence response in plants and animals against a common fungal pathogenCurrent research in microbial sciences · 2022Review
- Review
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tomato I-3 and I-7 genes confer resistance to Fusarium oxysporum f. sp. lycopersici (Fol) race 3 and were introgressed into the cultivated tomato, Solanum lycopersicum, from the wild relative Solanum pennellii. I-3 has been identified previously on chromosome 7 and encodes an S-receptor-like kinase, but little is known about I-7. Molecular markers have been developed for the marker-assisted breeding of I-3, but none are available for I-7. We used an RNA-seq and single nucleotide polymorphism (SNP) analysis approach to map I-7 to a small introgression of S. pennellii DNA (c. 210 kb) on chromosome 8, and identified I-7 as a gene encoding a leucine-rich repeat receptor-like protein (LRR-RLP), thereby expanding the repertoire of resistance protein classes conferring resistance to Fol. Using an eds1 mutant of tomato, we showed that I-7, like many other LRR-RLPs conferring pathogen resistance in tomato, is EDS1 (Enhanced Disease Susceptibility 1) dependent. Using transgenic tomato plants carrying only the I-7 gene for Fol resistance, we found that I-7 also confers resistance to Fol races 1 and 2. Given that Fol race 1 carries Avr1, resistance to Fol race 1 indicates that I-7-mediated resistance, unlike I-2- or I-3-mediated resistance, is not suppressed by Avr1. This suggests that Avr1 is not a general suppressor of Fol resistance in tomato, leading us to hypothesize that Avr1 may be acting against an EDS1-independent pathway for resistance activation. The identification of I-7 has allowed us to develop molecular markers for marker-assisted breeding of both genes currently known to confer Fol race 3 resistance (I-3 and I-7). Given that I-7-mediated resistance is not suppressed by Avr1, I-7 may be a useful addition to I-3 in the tomato breeder's toolbox.
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