ArticleTransplantation2016
Psychiatric Predictors of Long-term Transplant-Related Outcomes in Lung Transplant Recipients.
Article in Transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Psychological distress and self-psychological adjustment methods of lung transplant recipients: an overview of systematic reviews.BMC psychology · 2025Pooled it
- Anxiety disorders and all-cause mortality: systematic review and meta-analysis.Social psychiatry and psychiatric epidemiology · 2016Pooled it
- Telehealth interventions to improve outcomes in lung transplant recipients: Primary results of the INSPIRE-III randomized clinical trial.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025Trial
- Article
- Psychosocial challenges with transplantation.Current opinion in pulmonary medicine · 2026Review
- Risk of all-cause and cause-specific mortality, and suicide attempt in people with anxiety and stress-related disorders: a systematic review, meta-analysis and meta-regression analysis of 165 studies.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Frailty assessment and candidate optimization before cardiothoracic transplantation.JHLT open · 2026Article
- The Critical Role of Mental Health Specialists in Organ Transplantation Teams: An ELPAT Position Statement.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Medication adherence in thoracic transplant candidates.Frontiers in psychology · 2026Article
- Mapping the research trends and hotspots on lung transplant nursing: insights from bibliometric analysis.Journal of thoracic disease · 2025Article
- Article
- Palliative care for the cardiothoracic transplant recipient.JHLT open · 2025Article
- Family planning after transplantation: sex- and organ-related differences in the perception of medical counseling and social challenges.Archives of gynecology and obstetrics · 2025Article
- The development and psychometric evaluation of specific problem lists reflecting psychosocial distress of patients before and after solid organ transplantation.Frontiers in psychology · 2025Article
- The Association Between Patient-Level Factors and Physical Function in Lung Transplant Recipients.Cardiopulmonary physical therapy journal · 2024Article
- Chronic Postsurgical Pain Following Lung Transplantation: Characteristics, Risk Factors, Treatment, and Prevention: A Narrative Review.Pain and therapy · 2024Review
- Associations between the stanford integrated psychosocial assessment for transplant and one-year lung transplant medical and psychosocial outcomes.Journal of behavioral medicine · 2024Article
- Investigation of immunosuppressive treatment compliance, dyspnea, anxiety, and depression levels in lung transplant recipients: online interview.Frontiers in psychology · 2024Article
- Associations Between Psychiatric Diagnoses on Length of Stay and Mortality After Rib Fracture: A Retrospective Analysis.The Journal of surgical research · 2023Article
- Psychosocial Diagnosis and Treatment Before and After Organ Transplantation.Deutsches Arzteblatt international · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLong-term survival after lung transplantation remains poor, yet modifiable risk factors for late-term morbidity and mortality have yet to be identified. Because psychiatric disorders increase risk for poor health outcomes in many nontransplant chronic disease populations, lung recipients with depression or anxiety before or early after transplantation may be at heightened risk for late-term transplant-related morbidity and mortality.
methodsAmong 178 patients from a prospective study of mental health after lung transplantation, we identified 1-year survivors and examined whether they experienced major depression or anxiety disorders during that year as well as before transplantation. We used multivariable Cox regression to examine the relationship between these disorders and risk for subsequent bronchiolitis obliterans syndrome (BOS), mortality and graft loss for up to 15 years posttransplant, controlling for other known risk factors for the outcomes.
resultsOne hundred fifty-five recipients were studied. Recipients with posttransplant depression had an elevated risk of BOS (hazard ratio [HR], 1.91; 95% confidence interval [95% CI], 1.10-3.31), patient death (HR, 1.65; 95% CI, 1.01-2.71) and graft loss (HR, 1.75; 95% CI, 1.06-2.88). A trend toward reduced risk of BOS was observed in recipients with posttransplant anxiety (HR, 0.61; 95%CI, 0.37-1.00). Neither pretransplant disorder was related to risk for any outcome.
conclusionsEarly posttransplant depression increases risk for long-term transplant-related morbidity and mortality. Screening to identify depression should therefore be routine in posttransplant care. Although anxiety was not significantly associated with poor outcomes, screening for posttransplant anxiety should also be routine, to reduce patient distress. Research is needed to better understand mechanisms underlying depression-outcome associations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.