Evidence map›Paper›PMID 26176953›Full record

ArticlePloS one2015

Shape Transformations of Lipid Vesicles by Insertion of Bulky-Head Lipids.

Soichiro Tsuda, Tatsuya Sakakura, Satoshi Fujii, Hiroaki Suzuki, Tetsuya Yomo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Soichiro TsudaYomo Dynamical Micro-scale Reaction Environment Project, ERATO, Japan Science and Technology Agency, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tatsuya SakakuraGraduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Satoshi FujiiYomo Dynamical Micro-scale Reaction Environment Project, ERATO, Japan Science and Technology Agency, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Hiroaki SuzukiYomo Dynamical Micro-scale Reaction Environment Project, ERATO, Japan Science and Technology Agency, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan; Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tetsuya YomoYomo Dynamical Micro-scale Reaction Environment Project, ERATO, Japan Science and Technology Agency, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan; Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan; Graduate School of Frontier Biosciences, Osaka University, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Japan Science and Technology Agency · JPOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid vesicles, in particular Giant Unilamellar Vesicles (GUVs), have been increasingly important as compartments of artificial cells to reconstruct living cell-like systems in a bottom-up fashion. Here, we report shape transformations of lipid vesicles induced by polyethylene glycol-lipid conjugate (PEG lipids). Statistical analysis of deformed vesicle shapes revealed that shapes vesicles tend to deform into depended on the concentration of the PEG lipids. When compared with theoretically simulated vesicle shapes, those shapes were found to be more energetically favorable, with lower membrane bending energies than other shapes. This result suggests that the vesicle shape transformations can be controlled by externally added membrane molecules, which can serve as a potential method to control the replications of artificial cells.

Indexed as

MicellesPhosphatidylcholinesPhosphatidylethanolaminesPhosphatidylglycerolsPolyethylene GlycolsThermodynamicsUnilamellar Liposomes1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)1-palmitoyl-2-oleoylglycero-3-phosphoglycerol1-palmitoyl-2-oleoylphosphatidylcholineMicellesPhosphatidylcholinesPhosphatidylethanolaminesPhosphatidylglycerolsPolyethylene GlycolsUnilamellar Liposomes

Identifiers

PMID26176953
PMCPMC4503622
OpenAlexW1610199227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.