Evidence map›Paper›PMID 26176835›Full record

ArticleSao Paulo medical journal = Revista paulista de medicina

Liver transplantation in a patient with hepatitis B, C and D coinfection associated with hepatocellular carcinoma: a management strategy for a rare condition. Case report.

Lucas Carvalho Dantas, Tércio Genzini, Marcelo Perosa de Miranda, Regina Gomes dos Santos, Nilton Ghiotti de Siqueira, Judith Weirich, Cirley Maria de Oliveira Lobato

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Sao Paulo medical journal = Revista paulista de medicina. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucas Carvalho DantasHealth Sciences Center, Universidade Federal do Acre, Rio Branco, Acre, Brazil.
Tércio GenziniHospital Beneficência Portuguesa, São Paulo, São Paulo, Brazil.
Marcelo Perosa de MirandaHospital Beneficência Portuguesa, São Paulo, São Paulo, Brazil.
Regina Gomes dos SantosHospital Beneficência Portuguesa, São Paulo, São Paulo, Brazil.
Nilton Ghiotti de SiqueiraHospital das Clínicas do Acre, Rio Branco, Acre, Brazil.
Judith WeirichHospital das Clínicas do Acre, Rio Branco, Acre, Brazil.
Cirley Maria de Oliveira LobatoHospital das Clínicas do Acre, Rio Branco, Acre, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextOrthotopic liver transplantation (OLT) is the treatment of choice for end-stage liver disease. Cirrhosis due to hepatitis C infection is the leading indication for liver transplantation worldwide. However, patients who are given transplants because of viral liver diseases often present clinical coinfections, including hepatitis B together with hepatitis D. Currently, different strategies exist for patient management before and after liver transplantation, and these are based on different protocols developed by the specialized transplantation centers. CASE REPORT: We present a rare case of a 58-year-old man with chronic hepatitis B, C and D coinfection. The patient developed cirrhosis and hepatocellular carcinoma. His treatment comprised antiviral therapy for the three viruses and OLT. The patient's outcome was satisfactory.

conclusionOLT, in association with antiviral therapy using entecavir, which was administered before and after transplantation, was effective for sustained clearance of the hepatitis B and D viruses. A recurrence of hepatitis C infection after transplantation responded successfully to standard treatment comprising peginterferon alfa-2A and ribavirin.

Indexed as

Antiviral AgentsCarcinoma, HepatocellularCoinfectionHepatitis BHepatitis CHepatitis DHepatitis, Viral, HumanHumansInterferon-alphaLiver CirrhosisLiver NeoplasmsLiver TransplantationMaleMiddle AgedPolyethylene GlycolsRecombinant ProteinsAntiviral AgentsInterferon-alphapeginterferon alfa-2aPolyethylene GlycolsRecombinant ProteinsRibavirin

Identifiers

PMID26176835
PMCPMC10496563

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.