ArticleNeurogastroenterology and motility2015
Association of high dietary saturated fat intake and uncontrolled diabetes with constipation: evidence from the National Health and Nutrition Examination Survey.
Article in Neurogastroenterology and motility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Pooled it
- Article
- Extracellular Vesicle-Like Nanoparticles Present in Fermented Botanical Products Suppress Fat Absorption in the Gut.Journal of food science · 2025Article
- Association Between Caffeine Intake and Stool Frequency- or Consistency-Defined Constipation: Data From the National Health and Nutrition Examination Survey 2005-2010.Journal of neurogastroenterology and motility · 2025Article
- Association of anxiety status and anxiety duration with constipation in adult Americans: a cross-sectional study using data from the NHANES 2007-2010.BMC gastroenterology · 2025Article
- The association between oxidative balance score with constipation and diarrhea in US adults: a cross-sectional analysis of NHANES 2007-2010.BMC gastroenterology · 2025Article
- Association of the newly proposed dietary index for gut microbiota and constipation: a cross-sectional study from NHANES.Frontiers in nutrition · 2025Article
- Evaluating the link between the dietary intake of vitamin B and constipation: a population-based study.Frontiers in nutrition · 2025Article
- Exploring the association between cardiovascular health and bowel health.Scientific reports · 2024Article
- Gender differences in the association between dietary protein intake and constipation: findings from NHANES.Frontiers in nutrition · 2024Article
- LimosiLactobacillus pentosus Isolated from Mustard Relieves Drug-induced Constipation in Mice Fed a High-fat Diet by Modulating Enteric Neurotransmitter Function.Probiotics and antimicrobial proteins · 2023Article
- Association between dietary carotenoids intake and chronic constipation in American men and women adults: a cross-sectional study.BMC public health · 2023Article
- GI factors, potential to predict prostate motion during radiotherapy; a scoping review.Clinical and translational radiation oncology · 2023Article
- Association between dietary phosphorus intake and chronic constipation in adults: evidence from the National Health and Nutrition Examination Survey.BMC gastroenterology · 2023Article
- Zhishi Daozhi decoction alleviates constipation induced by a high-fat and high-protein diet via regulating intestinal mucosal microbiota and oxidative stress.Frontiers in microbiology · 2023Article
- Review
- Association of Stool Frequency and Consistency with the Risk of All-Cause and Cause-Specific Mortality among U.S. Adults: Results from NHANES 2005-2010.Healthcare (Basel, Switzerland) · 2022Article
- Association of sleep duration with chronic constipation among adult men and women: Findings from the National Health and Nutrition Examination Survey (2005-2010).Frontiers in neurology · 2022Article
- Association of Dietary Energy Intake With Constipation Among Men and Women: Results From the National Health and Nutrition Examination Survey.Frontiers in nutrition · 2022Article
- Association of dietary magnesium intake with chronic constipation among US adults: Evidence from the National Health and Nutrition Examination Survey.Food science & nutrition · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundConstipation is highly prevalent in the United States. The association of dietary fat intake with constipation has not been well studied. We recently reported that mice fed a high-fat diet had higher incidence of constipation than regular diet fed mice. The aim of this study was to assess if increased intake of dietary saturated fat in humans is also associated with higher risk of constipation and reduced stool frequency.
methodsAnalyses were based on data from 6207 adults (≥20 years) from the 2005-2006 and 2007-2008 cycles of the National Health and Nutrition Examination Surveys who had completed the bowel health questionnaire. Constipation was defined as a stool frequency of less than three times per week. Multivariable logistic regression analysis was used to calculate adjusted prevalence odds ratio (OR) estimates. Statistical analyses were performed using R and RStudio softwares. KEY
resultsThe prevalence of constipation in this sample was 3.1%. After multivariable adjustment high saturated fat remained associated with constipation. The OR for high saturated fat intake associated with constipation was much higher in diabetics above 65 years, especially in non-Hispanic blacks, females, and those with poor glycemic control, compared to the control group. CONCLUSIONS & INFERENCES: To the best of our knowledge, this is the first report to investigate the association of high saturated fat diet, bowel frequency, and diabetes. This study demonstrates that a high dietary saturated fat intake is associated with significant increase in the prevalence of constipation, especially in the uncontrolled diabetic, non-Hispanic black, female patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.