Evidence map›Paper›PMID 26175964›Full record

ArticleFrontiers in oncology2015

Socioeconomic Status and Childhood Leukemia Incidence in Switzerland.

Martin Adam, Claudia E Kuehni, Adrian Spoerri, Kurt Schmidlin, Fabienne Gumy-Pause, Pierluigi Brazzola, Nicole Probst-Hensch, Marcel Zwahlen

Abstract read
In one paragraph

Article in Frontiers in oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  3. Neighborhood Deprivation, Indoor Chemical Concentrations, and Spatial Risk for Childhood Leukemia.International journal of environmental research and public health · 2023
    Article
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  5. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin AdamSwiss Tropical and Public Health Institute , Basel , Switzerland ; University of Basel , Basel , Switzerland ; Institute of Social and Preventive Medicine, University of Bern , Bern , Switzerland.
Claudia E KuehniInstitute of Social and Preventive Medicine, University of Bern , Bern , Switzerland.
Adrian SpoerriInstitute of Social and Preventive Medicine, University of Bern , Bern , Switzerland.
Kurt SchmidlinInstitute of Social and Preventive Medicine, University of Bern , Bern , Switzerland.
Fabienne Gumy-PauseHaematology/Oncology Unit, Department of Paediatrics, University Hospital of Geneva , Geneva , Switzerland.
Pierluigi BrazzolaDepartment of Paediatrics, Ospedale San Giovanni , Bellinzona , Switzerland.
Nicole Probst-HenschSwiss Tropical and Public Health Institute , Basel , Switzerland ; University of Basel , Basel , Switzerland.
Marcel ZwahlenInstitute of Social and Preventive Medicine, University of Bern , Bern , Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Socioeconomic status (SES) discrepancies exist for child and adult cancer morbidity and are a major public health concern. In this Swiss population-based matched case-control study on the etiology of childhood leukemia, we selected the cases from the Swiss Childhood Cancer Registry diagnosed since 1991 and the controls randomly from census. We assigned eight controls per case from the 1990 and 2000 census and matched them by the year of birth and gender. SES information for both cases and controls was obtained from census records by probabilistic record linkage. We investigated the association of SES with childhood leukemia in Switzerland, and explored whether it varied with different definitions of socioeconomic status (parental education, living condition, area-based SES), time period, and age. In conditional logistic regression analyses of 565 leukemia cases and 4433 controls, we found no consistent evidence for an association between SES and childhood leukemia. The odds ratio comparing the highest with the lowest SES category ranged from 0.95 (95% CI: 0.71-1.26; P trend = 0.73) for paternal education to 1.37 (1.00-1.89; P trend = 0.064) for maternal education. No effect modification was found for time period and age at diagnosis. Based on this population-based study, which avoided participation and reporting bias, we assume the potential association of socioeconomic status and childhood leukemia if existing to be small. This study did not find evidence that socioeconomic status, of Switzerland or comparable countries, is a relevant risk factor or strong confounder in etiological investigations on childhood leukemia.

Indexed as

case–control studychildhood cancerleukemiarisk factorsocioeconomic status

Identifiers

PMID26175964
PMCPMC4485172

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.