SynthesisSchizophrenia bulletin2016
Deficits in Early Stages of Face Processing in Schizophrenia: A Systematic Review of the P100 Component.
Synthesis in Schizophrenia bulletin, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- A systematic review of studies that used NIRS to measure neural activation during emotion processing in healthy individuals.Social cognitive and affective neuroscience · 2021Pooled it
- Deficits in Emotional Face Processing Indexed by N170 Modulation in Chronic and in First Hospitalized Schizophrenia.Clinical EEG and neuroscience · 2026Article
- How psychological and descriptive narratives modulate the perception of facial emotional expressions: an event-related potentials (ERPs) study.Experimental brain research · 2025Article
- Weaker beta desynchronization indicates impaired emotion recognition in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Altered brain dynamics of facial emotion processing in schizophrenia: a combined EEG/fMRI study.Schizophrenia (Heidelberg, Germany) · 2025Article
- Disturbances in Auditory and Visual Perceptual Function in Schizophrenia: Patterns, Causes, and Consequences.Current topics in behavioral neurosciences · 2025Review
- Microstate Analyses to Study face Processing in Healthy Individuals and Psychiatric Disorders: A Review of ERP Findings.Brain topography · 2024Review
- The relationship between risk perception, anxiety and paranoia - A predictive model in a community sample.Journal of mood and anxiety disorders · 2024Article
- Could an evaluative conditioning intervention ameliorate paranoid beliefs? Self-reported and neurophysiological evidence from a brief intervention focused on improving self-esteem.Frontiers in psychiatry · 2024Article
- Aberrant Effective Connectivity During Eye Gaze Processing Is Linked to Social Functioning and Symptoms in Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Eye movements and ERP biomarkers for face processing problems in avoidant attachment-style individuals.Frontiers in behavioral neuroscience · 2023Article
- People with high schizotypy experience more illusions in the Pattern Glare Test: Consistent with the hyperexcitability hypothesis.The European journal of neuroscience · 2023Article
- Face pareidolia in male schizophrenia.Schizophrenia (Heidelberg, Germany) · 2022Article
- Unveiling the Associations between EEG Indices and Cognitive Deficits in Schizophrenia-Spectrum Disorders: A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
- An Event-Related Potential Investigation of Early Visual Processing Deficits During Face Perception in Youth at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2022Article
- Mismatch Negativity and P3a Impairment through Different Phases of Schizophrenia and Their Association with Real-Life Functioning.Journal of clinical medicine · 2021Article
- Socially induced negative affective knowledge modulates early face perception but not gaze cueing of attention.Psychophysiology · 2021Article
- Neural Oscillatory Abnormalities During Gaze Processing in Schizophrenia: Evidence of Reduced Theta Phase Consistency and Inter-areal Theta-Gamma Coupling.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- Dynamic causal modeling of eye gaze processing in schizophrenia.Schizophrenia research · 2021Article
- Transcranial direct current stimulation and emotion processing deficits in psychosis and depression.European archives of psychiatry and clinical neuroscience · 2021Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
introductionSchizophrenia is associated with deficits in face and affect recognition, which contribute to broader social functioning deficits. The present aim was to conduct a meta-analysis of early face processing in schizophrenia, as indexed by the P100 event-related potential component.
methodsTwelve studies (n = 328 patients with schizophrenia, n = 330 healthy controls) of the P100 component during face processing were evaluated by calculating Cohen's d for each study and overall weighted mean effect size (ES). In additional exploratory analyses, moderating influences of method and design were investigated, and the P100 component during face processing was evaluated based on valence: 5 studies (n = 225 patients, n = 225 controls) included neutral stimuli, 5 studies (n = 225 patients, n = 225 controls) included happy stimuli, and 4 studies (n = 209 patients, n = 209 controls) included fearful stimuli.
resultsThe amplitude of the P100 to face stimuli was smaller in patients relative to controls (ES = .41, P < .01). Methodological or design differences did not account for heterogeneity in ES. When split by valence, results indicate smaller P100 in patients relative to control subjects in response to neutral (ES = .32, P < .001) and happy (ES = .21, P < .05) stimuli, whereas there was no difference in response to fearful faces (ES = .09, P > .05). DISCUSSION: The results indicate that P100 amplitude in response to faces is smaller in patients with schizophrenia, showing that socially relevant visual processing deficits begin earlier in processing than previously suggested. Additionally, the exploratory analyses suggest emotional specificity in these deficits. Ramifications for our understanding of face processing deficits and treatment development are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.