Evidence map›Paper›PMID 26175358›Full record

Observational studyJournal of the American Heart Association2015

Trends in Gender Differences in Cardiac Care and Outcome After Acute Myocardial Infarction in Western Sweden: A Report From the Swedish Web System for Enhancement of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART).

Björn Redfors, Oskar Angerås, Truls Råmunddal, Petur Petursson, Inger Haraldsson, Christian Dworeck, Jacob Odenstedt, Dan Ioaness, Annika Ravn-Fischer, Peder Wellin and 7 more

Open access · goldAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of the American Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 142 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Review
  7. Sex-specific outcomes in myocardial infarction: a dual-cohort analysis using clinical and real-world data.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Review
  19. Observational
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Björn RedforsDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Oskar AngeråsDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Truls RåmunddalDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Petur PeturssonDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Inger HaraldssonDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Christian DworeckDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Jacob OdenstedtDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Dan IoanessDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Annika Ravn-FischerDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Peder WellinDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Helen SjölandDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Lale TokgozogluDepartment of Cardiology, Hacettepe University Hospital, Ankara, Turkey (L.T.).
Hans TygesenDepartment of Cardiology, Södra Älvsborgs Sjukhus, Borås, Sweden (H.T.).
Erik FrickDepartment of Cardiology, Skaraborg Hospital, Skövde, Sweden (E.F.).
Rickard RoupeDepartment of Cardiology, Allingsås Hospital, Allingsås, Sweden (R.R.).
Per AlbertssonDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Elmir OmerovicDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R., O.A., T., P.P., I.H., C.D., J.O., D.I., A.R.F., P.W., H.S., P.A., E.O.).
Sahlgrenska University Hospital · SEHacettepe University Hospital · TRSkaraborg Hospital · SESödra Älvsborg Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease is the most common cause of death for both genders. Debates are ongoing as to whether gender-specific differences in clinical course, diagnosis, and management of acute myocardial infarction (MI) exist. METHODS AND

resultsWe compared all men and women who were treated for acute MI at cardiac care units in Västra Götaland, Sweden, between January 1995 and October 2014 by obtaining data from the prospective SWEDEHEART (Swedish Web-System for Enhancement of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies) registry. We performed unadjusted and adjusted Cox proportional hazards and logistic regression analyses on complete case data and on imputed data sets. Overall, 48 118 patients (35.4% women) were diagnosed with acute MI. Women as a group had better age-adjusted prognosis than men, but this survival benefit was absent for younger women (aged <60 years) and for women with ST-segment elevation MI. Compared with men, younger women and women with ST-segment elevation MI were more likely to develop prehospital cardiogenic shock (adjusted odds ratio 1.67, 95% CI 1.30 to 2.16, P<0.001 and adjusted odds ratio 1.31, 95% CI 1.16 to 1.48, P<0.001) and were less likely to be prescribed evidence-based treatment at discharge (P<0.001 for β-blockers, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, statins, and P2Y12 antagonists). Differences in treatment between the genders did not decrease over the study period (P>0.1 for all treatments).

conclusionsWomen on average have better adjusted prognosis than men after acute MI; however, younger women and women with ST-segment elevation MI have disproportionately poor prognosis and are less likely to be prescribed evidence-based treatment.

Indexed as

AgedAged, 80 and overAge FactorsEvidence-Based MedicineFemaleGuideline AdherenceHealthcare DisparitiesHealth Status DisparitiesHospital MortalityHumansInternetLinear ModelsLogistic ModelsMaleMiddle AgedMyocardial Infarctionacute myocardial infarctionevidence‐based treatmentgendernon–ST‐segment elevation myocardial infarctionST‐segment elevation myocardial infarction

Identifiers

PMID26175358
PMCPMC4608084
OpenAlexW2159326935

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.