ArticleJournal of surgical oncology2015
Postoperative recurrence of papillary thyroid carcinoma with lymph node metastasis.
Article in Journal of surgical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.
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Who cites it
82 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical, Pathological, and Molecular Characteristics Correlating to the Occurrence of Radioiodine Refractory Differentiated Thyroid Carcinoma: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Clinical implications of Delphian lymph node metastasis in papillary thyroid carcinoma: a single-institution study, systemic review and meta-analysis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2019Pooled it
- Prophylactic bilateral central neck dissection should be evaluated based on prospective randomized study of 581 PTC patients.BMC endocrine disorders · 2022Trial
- Preoperative predictors of occult central lymph node metastasis in clinically node-negative papillary thyroid carcinoma: a common data model-based retrospective cohort study.Annals of surgical treatment and research · 2026Article
- Prognostic Comparison of Long-Term Outcomes and Nodal Recurrence for Persistent and Recurrent Differentiated Thyroid Cancer.Clinical and experimental otorhinolaryngology · 2026Article
- An insilico analysis: three upregulated microRNAs as potential diagnostic biomarkers of Papillary Thyroid Carcinoma (PTC).Journal of the Egyptian National Cancer Institute · 2026Article
- Organoid modeling identifies EDN1 as a potential oncogenic driver in papillary thyroid carcinoma via modulation of the Hippo-YAP signaling pathway.Journal of endocrinological investigation · 2026Article
- Article
- Clinical Risk Factor for Detected Distant Metastasis and Anaplastic Transformation After Reoperation in Recurrent/Persistent Differentiated Thyroid Cancer: A Retrospective Cohort Study.Laryngoscope investigative otolaryngology · 2025Article
- Article
- Predictive factors for failure in patients with N1b papillary thyroid carcinoma.World journal of surgical oncology · 2025Article
- Clinical Implications of Lymph Node Thyroglobulin in Papillary Thyroid Carcinoma Metastases: Independent from Thyroglobulin Antibody Interference.International journal of molecular sciences · 2025Article
- FNA-Tg improves the diagnostic efficacy of FNAC for PTC lateral cervical LN metastasis.Scientific reports · 2025Article
- Is secondAnnals of nuclear medicine · 2025Article
- Development and validation of a collagen signature to predict central lymph node metastasis in papillary thyroid cancer.Frontiers in endocrinology · 2025Article
- A clinical study of microwave ablation for cervical lymph node metastasis from papillary thyroid cancer.Frontiers in endocrinology · 2025Article
- FBP1 over-expression suppresses HIF-1α in papillary thyroid cancer.Scientific reports · 2024Article
- Prediction of bilateral thyroid carcinoma and lateral cervical lymph node metastasis in PTC patients with suspicious thyroid nodules.Endocrine · 2024Article
- Article
- Feasibility of active surveillance in patients with clinically T1b papillary thyroid carcinoma ≤1.5 cm in preoperative ultrasonography: MASTER study.European thyroid journal · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe purpose of this study was to retrospectively analyze the features of patients with papillary thyroid carcinoma (PTC) presenting with neck lymph node (LN) metastasis.
methodsThe study enrolled 909 patients with PTC who had undergone total thyroidectomy. After a median follow-up of 14.6 years, 73 (8.0%) patients died of thyroid cancer. A total of 536 patients had the tumor confined to the thyroid (intra-thyroid), 111 had lymph node (LN) metastasis, 225 showed soft tissue invasion, and 37 had distant metastasis.
resultsCompared with the intra-thyroid group, the group with LN metastases showed larger tumor size, higher postoperative thyroglobulin levels, advanced TNM stage, higher recurrence rates (5.2% vs. 31.5%), and higher disease-specific mortality (1.3% vs. 12.6%). Of the 111 patients with PTC and LN metastases, 35 (31.5%) were diagnosed with recurrence during a mean follow-up period of 16.9 ± 0.6 years. Among the 35 patients with recurrent PTC, 14 (40.0%) died of thyroid cancer. The mortality group was characterized by older, mostly male patients who presented with larger initial tumor size compared with survivors.
conclusionsIn patients with PTC, the rates of recurrence and cancer mortality were higher in the group with LN metastasis than that in the intra-thyroid tumor group.
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