Evidence map›Paper›PMID 26174817›Full record

ArticleThe Korean journal of parasitology2015

Sequence Variation in Superoxide Dismutase Gene of Toxoplasma gondii among Various Isolates from Different Hosts and Geographical Regions.

Shuai Wang, Aiping Cao, Xun Li, Qunli Zhao, Yuan Liu, Hua Cong, Shenyi He, Huaiyu Zhou

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of parasitology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shuai WangDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Aiping CaoDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Xun LiDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Ji'nan, Shandong, PR China.
Qunli ZhaoDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Yuan LiuDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Hua CongDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Shenyi HeDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Huaiyu ZhouDepartment of Parasitology, School of Medicine, Shandong University, Ji'nan, Shandong, PR China.
Shandong University · CNShandong Academy of Pharmaceutical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii, an obligate intracellular protozoan parasite of the phylum Apicomplexa, can infect all warm-blooded vertebrates, including humans, livestock, and marine mammals. The aim of this study was to investigate whether superoxide dismutase (SOD) of T. gondii can be used as a new marker for genetic study or a potential vaccine candidate. The partial genome region of the SOD gene was amplified and sequenced from 10 different T. gondii isolates from different parts of the world, and all the sequences were examined by PCR-RFLP, sequence analysis, and phylogenetic reconstruction. The results showed that partial SOD gene sequences ranged from 1,702 bp to 1,712 bp and A + T contents varied from 50.1% to 51.1% among all examined isolates. Sequence alignment analysis identified total 43 variable nucleotide positions, and these results showed that 97.5% sequence similarity of SOD gene among all examined isolates. Phylogenetic analysis revealed that these SOD sequences were not an effective molecular marker for differential identification of T. gondii strains. The research demonstrated existence of low sequence variation in the SOD gene among T. gondii strains of different genotypes from different hosts and geographical regions.

Indexed as

Genetic VariationAmino Acid SequenceAnimalsBase SequenceCatsGoatsHumansMolecular Sequence DataPhylogenyProtozoan ProteinsSequence AlignmentSheepSuperoxide DismutaseToxoplasmaToxoplasmosisToxoplasmosis, AnimalProtozoan ProteinsSuperoxide DismutasePCR-RFLPphylogenetic analysissequence variationsuperoxide dismutaseToxoplasma gondii

Identifiers

PMID26174817
PMCPMC4510687
OpenAlexW1952666032

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.