Evidence map›Paper›PMID 26174581›Full record

Trial reportBMC pediatrics2015

A pilot study to determine the short-term effects of milk with differing glycaemic properties on sleep among toddlers: a randomised controlled trial.

Snigdha Misra, Geok L Khor, Peter Mitchell, Samsul Haque, David Benton

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01589003 (An Intervention Study to Consider the Impact of Milk-products Differing in Their Glycaemic Properties on the Behaviour of Infants.), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01589003 naunknown statusnot on this map

An Intervention Study to Consider the Impact of Milk-products Differing in Their Glycaemic Properties on the Behaviour of Infants.

TypeinterventionalSponsorGeok Lin KhorRan2012 to 2013Enrolled70ConditionsMood Behaviour, Cognitive FunctionArmsLow Glycaemic index growing up milk, High GI growing up milk
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. The Effects of Milk and Dairy Products on Sleep: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Snigdha MisraDivision of Nutrition and Dietetics, International Medical University, 57000, Kuala Lumpur, Malaysia. snigdha_misra@imu.edu.my.
Geok L KhorDivision of Nutrition and Dietetics, International Medical University, 57000, Kuala Lumpur, Malaysia. geoklin_khor@imu.edu.my.
Peter MitchellDepartment of Psychology, University of Nottingham, Malaysia Campus, 43500, Semenyih, Selangor Darul Ehsan, Malaysia. Peter.Mitchell@nottingham.edu.my.
Samsul HaqueDepartment of Psychology, Monash University, Sunway Campus, 47500, Subang Jaya, Selangor, Malaysia. shamsul@monash.edu.my.
David BentonDepartment of Psychology, University of Swansea, Swansea, SA2 8PP, Wales, UK. d.benton@swansea.ac.uk.
International Medical University · MYMonash University · AUSwansea University · GBUniversity of Nottingham Malaysia Campus · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep is important for children as it directly impacts their mental and physical development. Sleep is not only influenced by the timing but also the macronutrient (carbohydrate and protein) content of meals. Glycaemic index (GI) and glycaemic load (GL) describe the quality of carbohydrates in a food and the burden of these foods on the body's blood glucose response. Diets with a high GI/GL may increase the risk of developing obesity and type 2 diabetes mellitus in adulthood. The present study is piloted to evaluate the short-term impact of milk products with differing glycaemic properties on the sleep patterns of toddlers.

methodsToddlers were recruited from various day care centres. Informed consent was obtained from both the mothers and the centres. A double-blind randomised controlled trial with a between-subjects design was adopted. The toddlers were randomised to either one of two types of milk with a differing GI ("Low" = 23 and "High = 65") for a period of 3.5 days. There were no other dietary restrictions imposed except that the enrolled child did not consume any other milk during the study period. The sleep patterns were recorded using a Phillips Actiwatch-2, which was worn on the wrist for 24 h over 4 days. The parameters used to measure the sleep pattern were sleep-onset latency (SOL), total sleep time (TST), wake after sleep onset (WASO) and sleep efficiency (SE).

resultsA total of 56 toddlers completed the study. The toddlers had a mean age of 19.9 ± 4.3 months. There were no significant differences (p > 0.05) between the two GI groups for SOL, TST, WASO and SE at the end of the feeding period.

conclusionsSleep patterns of toddlers on low-GI milk did not differ from those with high-GI milk consumed over a short period. Future studies should consider the glycaemic effects of other foods, along with milk with differing GI, consumed for a longer feeding duration.

trial registrationClinicalTrial.gov NCT01589003.

Indexed as

Glycemic LoadActigraphyAnimalsAnthropometryChild, PreschoolDouble-Blind MethodFemaleHumansInfantMaleMilkPilot ProjectsSleepSurveys and QuestionnairesTime Factors

Identifiers

PMID26174581
PMCPMC4502465
OpenAlexW1650827055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.