Evidence map›Paper›PMID 26173964›Full record

ArticleEuropean journal of human genetics : EJHG2016

The Greeks in the West: genetic signatures of the Hellenic colonisation in southern Italy and Sicily.

Sergio Tofanelli, Francesca Brisighelli, Paolo Anagnostou, George B J Busby, Gianmarco Ferri, Mark G Thomas, Luca Taglioli, Igor Rudan, Tatijana Zemunik, Caroline Hayward and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

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  5. The phenotypic state of biallelicERJ open research · 2025
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  7. The diverse genetic origins of a Classical period Greek army.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Phylogeographic review of Y chromosome haplogroups in Europe.International journal of legal medicine · 2021
    Review
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 15 institutions in 4 countries.

Sergio TofanelliDipartimento di Biologia, Università di Pisa, Pisa, Italy.
Francesca BrisighelliDepartment of Zoology, University of Oxford, Oxford, UK.
Paolo AnagnostouDipartimento di Biologia Ambientale, Università "La Sapienza", Roma, Italy.
George B J BusbyDepartment of Zoology, University of Oxford, Oxford, UK.
Gianmarco FerriDipartimento ad Attività Integrata di Laboratori, Anatomia Patologica, Medicina Legale, U.O. Struttura Complessa di Medicina Legale, Università di Modena e Reggio Emilia, Modena, Italy.
Mark G ThomasDepartment of Genetics, Evolution and Environment, University College London, London, UK.
Luca TaglioliDipartimento di Biologia, Università di Pisa, Pisa, Italy.
Igor RudanCentre for Population Health Sciences, The University of Edinburgh Medical School, Scotland, UK.
Tatijana ZemunikDepartment of Medical Biology, University of Split, School of Medicine, Split, Croatia.
Caroline HaywardMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Western General Hospital, Edinburgh, UK.
Deborah BolnickMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Western General Hospital, Edinburgh, UK.
Valentino RomanoDipartimento di Fisica e Chimica, Università di Palermo, Palermo, Italy.
Francesco CaliDipartimento di Fisica e Chimica, Università di Palermo, Palermo, Italy.
Donata LuiselliLaboratorio di Antropologia Molecolare, Dipartimento di Scienze Biologiche, Geologiche e Ambientali, Università di Bologna, Bologna, Italy.
Gillian B ShepherdA.D. Trendall Research Centre for Ancient Mediterranean Studies, La Trobe University, Melbourne, Victoria, Australia.
Sebastiano TusaSopraintendenza del mare, Palermo, Italy.
Antonino FacellaSoprintendenza per i Beni Archeologici della Calabria, Reggio Calabria, Italy.
Cristian CapelliDepartment of Zoology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-9348-9084
University of Pisa · ITWestern General Hospital · GBCentre for Human Genetics · GBExperimental Station for the Industry of the Essential Oils and Citrus Products · ITI.R.C.C.S. Oasi Maria SS · ITLa Trobe University · AUSapienza University of Rome · ITUniversità Cattolica del Sacro Cuore · ITUniversity College London · GBUniversity of Bologna · ITUniversity of Edinburgh · GBUniversity of Modena and Reggio Emilia · ITUniversity of Oxford · GBUniversity of Palermo · ITUniversity of Split · HR

Funding

Medical Research Council MC_PC_U127561128
6 · The paper itself

Abstract

Greek colonisation of South Italy and Sicily (Magna Graecia) was a defining event in European cultural history, although the demographic processes and genetic impacts involved have not been systematically investigated. Here, we combine high-resolution surveys of the variability at the uni-parentally inherited Y chromosome and mitochondrial DNA in selected samples of putative source and recipient populations with forward-in-time simulations of alternative demographic models to detect signatures of that impact. Using a subset of haplotypes chosen to represent historical sources, we recover a clear signature of Greek ancestry in East Sicily compatible with the settlement from Euboea during the Archaic Period (eighth to fifth century BCE). We inferred moderate sex-bias in the numbers of individuals involved in the colonisation: a few thousand breeding men and a few hundred breeding women were the estimated number of migrants. Last, we demonstrate that studies aimed at quantifying Hellenic genetic flow by the proportion of specific lineages surviving in present-day populations may be misleading.

Indexed as

Genetics, PopulationDemographyFemaleGeographyGreeceHaplotypesHumansMaleMutationPhylogenySicily

Identifiers

PMID26173964
PMCPMC4757772
OpenAlexW1884555388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.