Evidence map›Paper›PMID 26173865›Full record

ArticleEuropean journal of clinical nutrition2016

A comparison of the nutritional status between adult celiac patients on a long-term, strictly gluten-free diet and healthy subjects.

M Barone, N Della Valle, R Rosania, A Facciorusso, A Trotta, F P Cantatore, S Falco, S Pignatiello, M T Viggiani, A Amoruso and 3 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04351828 (The Investigation of Nutritional Status, Intestinal Permeability and Quality of Life in People With Celiac Disease), which is not on this map. Cited by 47 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 9 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04351828 completednot on this mapstarted 2018, after this paper: background citation

The Investigation of Nutritional Status, Intestinal Permeability and Quality of Life in People With Celiac Disease

TypeobservationalSponsorMarmara UniversityRan2018 to 2019Enrolled44ConditionsCeliac Disease, Nutritional Deficiency, Quality of LifeArmsBlood draw once a time
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 9 syntheses or guidelines pooled it, 99 citations in OpenAlex.

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  19. The Investigation of Nutritional Status, Intestinal Permeability, and Quality of Life in People with Celiac Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

M BaroneGastroenterology Unit, Department of Emergency and Organ Transplantation (D.E.T.O.), University of Bari, Bari, Italy.
N Della ValleGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
R RosaniaGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
A FacciorussoGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
A TrottaRheumatology Units, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
F P CantatoreRheumatology Units, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
S FalcoGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
S PignatielloGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
M T ViggianiGastroenterology Unit, Department of Emergency and Organ Transplantation (D.E.T.O.), University of Bari, Bari, Italy.
A AmorusoGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
R De FilippisGastroenterology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
A Di LeoGastroenterology Unit, Department of Emergency and Organ Transplantation (D.E.T.O.), University of Bari, Bari, Italy.
R FrancavillaDepartment of Biomedicina dell'Età Evolutiva, University of Bari, Bari, Italy.
University of Foggia · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThere are conflicting data on the effect of a gluten-free diet (GFD) on the nutritional status of celiac patients. In the present study, we evaluated, in adult celiac patients, the influence of a long-term, strictly GFD on their nutritional status and compared it with matched healthy volunteers. SUBJECTS/

methodsOur study included 39 celiac patients and 39 healthy volunteers. The body mass index (BMI) of patients and controls was evaluated at enrollment, while the patients' BMI before the GFD was retrieved from clinical records. In addition, at enrollment, in both groups, we compared BMI, fat mass (FM), bone mineral density (BMD), as well as their dietary intake, recorded on a 7-day diary.

resultsAt the time of diagnosis, the majority of celiac patients (82.0%) had a normal BMI or were overweight, while 10.3% were malnourished. After the GFD, patients with a normal BMI showed a significant weight increase (P=0.002), but none of them switched in the overweight or obese category. Two (50%) of the four malnourished patients achieved a normal BMI. Controls and patients on a GFD had a similar BMI, FM, BMD and total calorie intake, but the amount of lipids and fiber intake was significantly different in the two groups (P=0.003 and P<0.0001, respectively).

conclusionsOur study demonstrates that a GFD is able to improve the nutritional status of celiac patients without inducing overweight or obesity. Our findings are related to a celiac population adopting a GFD based on a Mediterranean-type diet.

Indexed as

Body Mass IndexDiet, Gluten-FreeNutritional StatusWeight GainAdipose TissueAdultBody WeightBone DensityCase-Control StudiesCeliac DiseaseDietary FatsDietary FiberEnergy IntakeFemaleHealthy VolunteersHumansDietary FatsDietary Fiber

Identifiers

PMID26173865
OpenAlexW1556039423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.