Evidence map›Paper›PMID 26173617›Full record

ArticleAlcoholism, clinical and experimental research2015

Behavioral Impulsivity and Risk-Taking Trajectories Across Early Adolescence in Youths With and Without Family Histories of Alcohol and Other Drug Use Disorders.

Donald M Dougherty, Sarah L Lake, Charles W Mathias, Stacy R Ryan, Bethany C Bray, Nora E Charles, Ashley Acheson

Open access · greenAbstract readComparative Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  17. The Development of Impulsivity and Sensation Seeking: Associations with Substance Use among At-Risk Adolescents.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2020
    Article
  18. Behavioral processes and risk for problem substance use in adolescents.Pharmacology, biochemistry, and behavior · 2020
    Review
  19. Article
  20. Changes in delay discounting, substance use, and weight status across adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Donald M DoughertyDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Sarah L LakeDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Charles W MathiasDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Stacy R RyanDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Bethany C BrayThe Methodology Center, The Pennsylvania State University, State College, Pennsylvania.
Nora E CharlesDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Ashley AchesonDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
The University of Texas Health Science Center at San Antonio · USPennsylvania State University · US

Funding

THE REFINEMENT &APPLICATION OF MEDICAL DECISION MAKING IN PREVENTION SCIENCESP50DA010075 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI LANZA, STEPHANIE T · 1996 to 2014
$24.5M
Consequences of Substance Use on the Development of Impulse ControlR01DA026868 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DOUGHERTY, DONALD M, ROACHE, JOHN D · 2010 to 2021
$6.4M
Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2M
Relating brain maturation to impulse control and substance use developmentR01DA033997 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ACHESON, ASHLEY, DOUGHERTY, DONALD M · 2012 to 2016
$2.5M
NIDA NIH HHS P50 DA010075NIDA NIH HHS R01 DA026868NIDA NIH HHS R01-DA026868NIDA NIH HHS R01 DA033997NIDA NIH HHS R01-DA033997NIDA NIH HHS T32 DA031115NIDA NIH HHS T32-DA031115
6 · The paper itself

Abstract

backgroundYouths with family histories of alcohol and other drug use disorders (FH+) are at increased susceptibility for developing substance use disorders relative to those without such histories (FH-). This vulnerability may be related to impaired adolescent development of impulse control and elevated risk-taking. However, no previous studies have prospectively examined impulse control and risk-taking in FH+ youth across adolescence.

methodsA total of 386 pre-adolescents (305 FH+, 81 FH-; aged 10 to 12) with no histories of regular alcohol or other drug use were compared on behavioral measures of impulsivity including delay discounting, response initiation (Immediate Memory Task), response inhibition impulsivity (GoStop Impulsivity Paradigm), and risk-taking (Balloon Analogue Risk Task-Youth). Youths completed these laboratory tasks every 6 months, allowing for the examination of 10- to 15-year-olds. Hierarchical linear modeling was used to characterize the development of impulse control and risk-taking as shown in performance of these tasks throughout adolescence.

resultsWe found that (i) FH+ youths had increased levels of delay discounting and response inhibition impulsivity at study entry; (ii) regardless of FH status, all youths had relatively stable delay discounting across time, improvements in response inhibition and response initiation impulsivity, and increased risk-taking; and (iii) although FH+ youths had increased response inhibition impulsivity at pre-adolescence, these differences were negligible by mid-adolescence.

conclusionsHeightened delay discounting in FH+ pre-adolescents coupled with normal adolescent increases in risk-taking may contribute to their increased susceptibility toward problem substance use in adolescence.

Indexed as

Impulsive BehaviorRisk-TakingAdolescentAdolescent BehaviorAlcoholismChildDelay DiscountingFemaleHumansLongitudinal StudiesMaleProspective StudiesSubstance-Related DisordersAdolescent DevelopmentDelay DiscountingFamily HistoryImpulsivityRisk-TakingSubstance Use Disorders

Identifiers

PMID26173617
PMCPMC4630668
OpenAlexW2165653365

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.