Trial reportSurgical endoscopy2016
Double-scope per oral endoscopic myotomy (POEM): a prospective randomized controlled trial.
Trial report in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Updated Systematic Review of Achalasia, with a Focus on POEM Therapy.Digestive diseases and sciences · 2020Pooled it
- Gastric myotomy length affects severity but not rate of post-procedure reflux: 3-year follow-up of a prospective randomized controlled trial of double-scope per-oral endoscopic myotomy (POEM) for esophageal achalasia.Surgical endoscopy · 2020Trial
- Endoscopic Pseudo-dilation of Esophagogastric Junction During Peroral Endoscopic Myotomy: (With Video).DEN open · 2027Article
- Enhanced Visualization of the Distal Myotomy Endpoint during Peroral Endoscopic Myotomy Using Indocyanine Green With Infrared Imaging.DEN open · 2026Article
- Saudi Gastroenterology Association (SGA) clinical care pathway and standards of care for peroral endoscopic myotomy (POEM) in achalasia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Peroral endoscopic myotomy in spastic esophageal disorders: Clinical outcomes and optimal approaches.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Article
- Phase concept: Novel dynamic endoscopic assessment of intramural antireflux mechanisms (with video).Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Article
- Association of gastric myotomy length in peroral endoscopic myotomy (POEM) with gastro-esophageal junction distensibility measured by Endoluminal Functional Lumen Imaging Probe (EndoFLIP).Esophagus : official journal of the Japan Esophageal Society · 2024Article
- Impedance planimetry during per-oral endoscopic myotomy is associated with decreased inadvertent capnoperitoneum.Surgical endoscopy · 2024Article
- Role of endoscopy in patients with achalasia.Clinical endoscopy · 2023Review
- Endoscopic submucosal dissection using an ultrathin endoscope for superficial pharyngeal cancer: a prospective feasibility study (with video).Endoscopy international open · 2023Article
- Updates in the Field of Submucosal Endoscopy.Life (Basel, Switzerland) · 2022Review
- High Eckardt score and previous treatment were associated with poor postperoral endoscopic myotomy pain control: A retrospective study.World journal of clinical cases · 2022Article
- Safety and effectiveness of sling fiber preservation POEM to reduce severe post-procedural erosive esophagitis.Surgical endoscopy · 2022Article
- POEM, GPOEM, and ZPOEM.Digestive diseases and sciences · 2022Review
- Gastro-esophageal reflux disease (GERD) after peroral endoscopic myotomy (POEM).Surgical endoscopy · 2022Article
- Long-term clinical results of per-oral endoscopic myotomy (POEM) for achalasia: First report of more than 10-year patient experience as assessed with a questionnaire-based survey.Endoscopy international open · 2021Article
- Treatment challenges of sigmoid-shaped esophagus and severe achalasia.Annals of medicine and surgery (2012) · 2021Review
- Peroral endoscopic myotomy alone is effective for esophageal motility disorders and esophageal epiphrenic diverticulum: a retrospective single-center study.Surgical endoscopy · 2020Article
- Per-oral endoscopic myotomy (POEM) for a sigmoid type of achalasia: short-term outcomes and changes in the esophageal angle.Surgical endoscopy · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince its introduction in 2010, per oral endoscopic myotomy (POEM) has offered an alternative to laparoscopic Heller myotomy for the treatment of achalasia. A gastric myotomy length of 3 cm has been recommended; however, it can be difficult to ensure that adequate submucosal dissection has been performed during the procedure. Commonly accepted endoscopic markers of the gastric side can be inaccurate, particularly in patients with prior endoscopic treatments, such as balloon dilation or Botox injection of the lower esophageal sphincter. We hypothesized that the use of a second endoscope would result in a more complete gastric myotomy.
methodsOne hundred consecutive achalasia patients were randomized into single- and double-scope POEM groups. In the treatment group, a second endoscope was used to obtain a retroflexed view of the gastric cardia, while the dissecting scope transilluminated from the end of the submucosal tunnel. Prospectively collected data were analyzed, including myotomy lengths, procedure times, adverse events, and clinical outcomes.
resultsPOEM was completed with high rates of technical (98-100%) and clinical success (93-97%) in both groups, with a low rate of serious adverse events (2%). The second endoscope resulted in a 17 min increase in procedure time (94 vs. 77 min), myotomy extension in 34% of cases, and an increase in the average gastric myotomy length from 2.6 to 3.2 cm (p = 0.01).
conclusionA second endoscope is useful for ensuring a complete gastric myotomy during POEM. With minimal increase in procedure time and no increase in morbidity, it may be particularly useful in cases of sigmoid esophagus or otherwise altered anatomy that makes identification of the gastroesophageal junction difficult.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.