Evidence map›Paper›PMID 26173246›Full record

ArticlePerspectives on psychological science : a journal of the Association for Psychological Science2014

Your Brain on Insulin: From Heresy to Dogma.

Ewan McNay

Open access · greenAbstract read
In one paragraph

Article in Perspectives on psychological science : a journal of the Association for Psychological Science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ewan McNaySUNY Albany - Behavioral Neuroscience/Psychology emcnay@albany.edu.
University at Albany, State University of New York · US

Funding

Insulin in the hippocampus: memory enhancement and impact of type 2 diabetesR01DK077106 · NIDDK · YALE UNIVERSITY · PI MCNAY, EWAN C · 2007 to 2011
$1.4M
NIDDK NIH HHS R01 DK077106
6 · The paper itself

Abstract

As recently as 1988, the idea that insulin might regulate cognitive and neural functions was, if not quite heretical, still seen as unlikely. As our ability to measure metabolic and molecular changes in the brain has improved, the hippocampus in particular has been revealed as a primary target for insulin. Today insulin is established as a key regulator of hippocampal fuel supply and a critical component of memory formation and storage within the hippocampus. Brain insulin signaling is a target for therapeutic intervention in patients with neuropsychological conditions such as Alzheimer's disease.

Indexed as

Alzheimer’s diseasediabeteshippocampusinsulinmemory

Identifiers

PMID26173246
PMCPMC5674786
OpenAlexW2103039456

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.