Evidence map›Paper›PMID 26173074›Full record

ArticleMenopause (New York, N.Y.)2016

Predictors of impact of vaginal symptoms in postmenopausal women.

Mary M Hunter, Sanae Nakagawa, Stephen K Van Den Eeden, Miriam Kuppermann, Alison J Huang

Abstract read
In one paragraph

Article in Menopause (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Associations between menopause and body image.Przeglad menopauzalny = Menopause review · 2025
    Article
  6. Genitourinary syndrome in menopause: Impact of vaginal symptoms.Turkish journal of obstetrics and gynecology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Effect of the Fractional COJournal of lasers in medical sciences · 2020
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mary M Hunter1Department of Physiological Nursing, School of Nursing, University of California San Francisco, San Francisco, CA 2Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA 3Division of Research, Kaiser Permanente Northern California, Department of Urology, University of California San Francisco, San Francisco, CA 4Department of Medicine, University of California San Francisco, San Francisco, CA.
Sanae Nakagawa
Stephen K Van Den Eeden
Miriam Kuppermann
Alison J Huang

Funding

Urinary Incontinence: Reproductive/Hormonal Risk FactorsP50DK064538 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BROWN, JEANETTE S · 2002 to 2011
$11.5M
A Multidimensional Approach to Urogenital Aging in Older WomenK23AG038335 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, ALISON · 2011 to 2013
$504k
The Impact of Vaginal Atrophy Symptoms on Quality of Life in Postmenopausal WomenR03AG035207 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, ALISON · 2010 to 2011
$101k
NIA NIH HHS 1K23AG038335NIA NIH HHS 1R03AG035207NIA NIH HHS K23 AG038335NIA NIH HHS R03 AG035207NIDDK NIH HHS P50 DK064538
6 · The paper itself

Abstract

objectiveThis study aims to identify factors associated with greater impact of vaginal symptoms on the functioning and well-being of postmenopausal women.

methodsPostmenopausal women who reported vaginal dryness, itching, irritation, or pain with sexual activity completed the multidimensional Day-to-day Impact of Vaginal Aging (DIVA) questionnaire and underwent assessment of multiple sociodemographic and clinical factors that have the potential to influence the impact of vaginal symptoms. Multivariable linear regression analyses examined relationships between selected participant characteristics and DIVA scale scores assessing symptom impact on activities of daily living, emotional well-being, self-concept and body image, and sexual functioning.

resultsAmong 745 symptomatic participants, the mean (SD) age was 56 (9) years, and 66% were racial/ethnic minorities. Women with comorbid depression reported greater impact of vaginal symptoms on all dimensions of functioning and well-being measured by the DIVA questionnaire (11%-22% estimated increase in impact scores associated with every three-point increase in Hospital and Anxiety Depression Scale scores). Women with urinary incontinence also reported greater impact of vaginal symptoms on activities of daily living, emotional well-being, and self-concept and body image (27%-37% estimated increase in impact scores). Age, partner status, frequency of sexual activity, general health, and body mass index also predicted greater impact on at least one domain.

conclusionsFindings suggest that special efforts should be made to identify and treat vaginal symptoms in postmenopausal women known to have depression or urinary incontinence, as these women may experience greater impact of vaginal symptoms on multiple domains of functioning and quality of life.

Indexed as

Quality of LifeActivities of Daily LivingAgedAge FactorsAgingBody ImageBody Mass IndexDepressionEmotionsEthnicityFemaleHumansMiddle AgedPostmenopauseSelf ConceptSexual Behavior

Identifiers

PMID26173074
PMCPMC4684983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.