ArticlePLoS genetics2015
A Genome Scan for Genes Underlying Microgeographic-Scale Local Adaptation in a Wild Arabidopsis Species.
Article in PLoS genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 79 citations in OpenAlex.
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- Unique genetic bases of repeated life-history divergence associated with high altitude adaptation inbioRxiv : the preprint server for biology · 2025Article
- Population Genomics Reveals Demographic History and Climate Adaptation in Japanese Arabidopsis halleri.Plant & cell physiology · 2025Article
- A multiple computational spatial analysis of genetic, morphological, and anatomical diversity in Pteris cretica L. (Pteridaceae) geographical populations.BMC plant biology · 2025Article
- Divergent functional traits and gene expression profiles in native and encroaching plant species across an alpine elevational gradient.Frontiers in plant science · 2025Article
- The genetic architecture of repeated local adaptation to climate in distantly related plants.Nature ecology & evolution · 2024Article
- Genomics of ecological adaptation in Canary IslandEcology and evolution · 2024Article
- Does selection occur at the intermediate zone of two insufficiently isolated populations? A whole-genome analysis along an altitudinal gradient.Journal of plant research · 2023Article
- Comparison between the Gametophyte and the Sporophyte Transcriptomes of the Endangered FernGenes · 2023Article
- Climate-Driven Adaptive Differentiation inGenes · 2022Article
- Multi-Omics Approaches Revealed the Associations of Host Metabolism and Gut Microbiome With Phylogeny and Environmental Adaptation in Mountain Dragons.Frontiers in microbiology · 2022Article
- Genomic basis of parallel adaptation varies with divergence inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Altitudinal differentiation in the leaf wax-mediated flowering bud protection against frost in a perennial Arabidopsis.Oecologia · 2021Article
- Population genomic structure of Eurasian and African foxtail millet landrace accessions inferred from genotyping-by-sequencing.The plant genome · 2021Article
- Genomic signatures of convergent adaptation to Alpine environments in three Brassicaceae species.Molecular ecology · 2020Article
- Genetic consequences of being a dwarf: do evolutionary changes in life-history traits influence gene flow patterns in populations of the world's smallest goldenrod?Annals of botany · 2020Article
- Parallel Alpine Differentiation inFrontiers in plant science · 2020Article
- Review
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adaptive divergence at the microgeographic scale has been generally disregarded because high gene flow is expected to disrupt local adaptation. Yet, growing number of studies reporting adaptive divergence at a small spatial scale highlight the importance of this process in evolutionary biology. To investigate the genetic basis of microgeographic local adaptation, we conducted a genome-wide scan among sets of continuously distributed populations of Arabidopsis halleri subsp. gemmifera that show altitudinal phenotypic divergence despite gene flow. Genomic comparisons were independently conducted in two distinct mountains where similar highland ecotypes are observed, presumably as a result of convergent evolution. Here, we established a de novo reference genome and employed an individual-based resequencing for a total of 56 individuals. Among 527,225 reliable SNP loci, we focused on those showing a unidirectional allele frequency shift across altitudes. Statistical tests on the screened genes showed that our microgeographic population genomic approach successfully retrieve genes with functional annotations that are in line with the known phenotypic and environmental differences between altitudes. Furthermore, comparison between the two distinct mountains enabled us to screen out those genes that are neutral or adaptive only in either mountain, and identify the genes involved in the convergent evolution. Our study demonstrates that the genomic comparison among a set of genetically connected populations, instead of the commonly-performed comparison between two isolated populations, can also offer an effective screening for the genetic basis of local adaptation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.