Evidence map›Paper›PMID 26171787›Full record

ArticleAutism research : official journal of the International Society for Autism Research2016

Reduced Efficiency and Capacity of Cognitive Control in Autism Spectrum Disorder.

Melissa-Ann Mackie, Jin Fan

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. "Don't talk to me like I am an illness": exploring patients' needs using the communication passport in an eating disorder service.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2025
    Article
  5. What Are You Worried About? Content and Extent of Worry in Autistic Adults.Journal of autism and developmental disorders · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Melissa-Ann MackieGraduate Center, The City University of New York, New York, NY, 10016.
Jin FanDepartment of Psychology, Queens College, The City University of New York, Queens, NY, 11367.

Funding

Uncertainty, Cognitive Control, and the BrainR01MH094305 · NIMH · QUEENS COLLEGE · PI FAN, JIN · 2012 to 2016
$1.7M
Anterior Cingulate and Fronto-Insular Related Brain Networks in AutismR21MH083164 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAN, JIN · 2008 to 2009
$417k
NIMH NIH HHS R01 MH094305NIMH NIH HHS R21 MH083164
6 · The paper itself

Abstract

Cognitive control constrains mental operations to prioritize information that reaches conscious awareness and is essential to flexible, adaptive behavior under conditions of uncertainty. Cognitive control can be compromised by neurodevelopmental disorders such as autism spectrum disorder (ASD), which is characterized by the presence of social and communicative deficits, and restricted interests/repetitive behaviors. Although prior investigations have attempted to elucidate the nature of cognitive control in ASD, whether there is an underlying information processing deficit associated with cognitive control remains unclear. This study challenged cognitive control in 15 high-functioning adults with ASD and 15 typically developing (TD) controls using three novel tasks designed to systematically manipulate uncertainty. We aimed to investigate the efficiency of cognitive control in sequential information processing, cognitive control of nonsequential information processing across a range of cognitive loads and cognitive control capacity under time constraint. Results demonstrated that the ASD group performed less efficiently on sequential and nonsequential information processing, and had reduced cognitive control capacity under time constraint relative to the TD group. These findings suggest that inefficient cognitive control of information processing may be a fundamental deficit in ASD.

Indexed as

AdolescentAdultAutism Spectrum DisorderCognitionCognition DisordersExecutive FunctionFemaleHumansMaleNeuropsychological TestsYoung Adultautismcognitive controlexecutive functionsinformation processinginformation theory

Identifiers

PMID26171787
PMCPMC4713391

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.