Evidence map›Paper›PMID 26171305›Full record

ArticleEuropean journal of pediatric surgery reports2015

The Appendix and Aganglionosis. A Note of Caution-How the Histology Can Mislead the Surgeon in Total Colonic Hirschsprung Disease.

Victoria Alison Lane, Marc A Levitt, Peter Baker, Peter Minneci, Katherine Deans

Open access · goldAbstract readCase Reports
In one paragraph

Article in European journal of pediatric surgery reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Observational
  2. Surgical pathology of Hirschsprung disease (HSCR).World journal of pediatric surgery · 2025
    Review
  3. Article
  4. Skip Segment Hirschsprung Disease Managed by Pull-Through of the Right Colon.European journal of pediatric surgery reports · 2021
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Victoria Alison LaneCenter for Colorectal and Pelvic Reconstruction, Nationwide Children's Hospital, Columbus, Ohio, United States ; Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, Ohio, United States.
Marc A LevittCenter for Colorectal and Pelvic Reconstruction, Nationwide Children's Hospital, Columbus, Ohio, United States.
Peter BakerDepartment of Pathology, Nationwide Children's Hospital, Columbus, Ohio, United States.
Peter MinneciCenter for Colorectal and Pelvic Reconstruction, Nationwide Children's Hospital, Columbus, Ohio, United States ; Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, Ohio, United States.
Katherine DeansCenter for Colorectal and Pelvic Reconstruction, Nationwide Children's Hospital, Columbus, Ohio, United States ; Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, Ohio, United States.
Nationwide Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a child with presumed total colonic Hirschsprung disease (HD) to highlight the problems the surgeon is likely to encounter if he/she relies on the appendix alone for histopathologic diagnosis. A newborn male infant, who was presumed to have total colonic aganglionosis when the appendix was found to be aganglionic at the time of initial exploratory laparoscopy, was managed with an ileostomy in the newborn period; however, at the time of his planned pull-through procedure, the rectal biopsy revealed normal ganglion cells. The child was subsequently managed with ileostomy closure and observed for normal feeding and stooling prior to discharge home. We discuss the histopathologic findings of the appendix in separate cases of confirmed total colonic HD seen in our center, and review the normal histopathologic findings of the appendix.

Indexed as

appendixHirschsprunghistopathology

Identifiers

PMID26171305
PMCPMC4487127
OpenAlexW816686196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.