ArticleAmerican journal of blood research2015
Type B lactic acidosis: a rare but life threatening hematologic emergency. A case illustration and brief review.
Article in American journal of blood research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Spontaneous cardiac rupture as the initial presentation of acute myeloid leukaemia complicated by malignant lactic acidosis: a case report.European heart journal. Case reports · 2026Article
- Can Serum Lactate on Admission to Intensive Care Predict Length of Stay? A Retrospective Analysis of Critically Ill Paediatric Oncology Patients.Journal of paediatrics and child health · 2025Observational
- Tumor-Associated Lactic Acidosis and Early Death in Patients With Lymphoma.Cancer medicine · 2025Article
- Successful management of type B lactic acidosis in metastatic cervical neuroendocrine carcinoma: A case report.Oncology letters · 2025Article
- A rare case of diffuse large B-cell lymphoma masquerading as Guillain Barre syndrome, Warburg phenomenon and hemophagocytic lymphohistiocytosis.Ecancermedicalscience · 2025Article
- The CILLO-E Hypothesis: Erythrocyte-Driven Acidosis and Early Eryptosis as Drivers of Cancer-Associated Anemia.Frontiers in oncology · 2025Article
- Article
- Lactic acidosis in a patient with cancer.Clinical medicine (London, England) · 2023Article
- Clinical Warburg effect in lymphoma patients admitted to intensive care unit.Annals of intensive care · 2023Article
- Clinical presentation of Warburg effect in aggressive lymphoma: a case report.Journal of medical case reports · 2023Article
- Need for intensive care admission based on point-of-care measurement of serum lactate levels in early trauma care.Journal of clinical orthopaedics and trauma · 2022Article
- An Oncological Emergency: Severe Type B Lactic Acidosis From Warburg Effect in Diffuse Large B-cell Lymphoma.Cureus · 2022Article
- Metabolic Biomarkers in B-Cell Lymphomas for Early Diagnosis and Prediction, as Well as Their Influence on Prognosis and Treatment.Diagnostics (Basel, Switzerland) · 2022Review
- Article
- Lactic acidosis and hypoglycemia as markers of disease progression of multiple myeloma: A case report.EJHaem · 2021Article
- Non-Hodgkin Lymphoma Metabolism.Advances in experimental medicine and biology · 2021Article
- Severe type-B lactic acidosis in a patient with bilateral renal Burkitt's lymphoma.Clinical nephrology. Case studies · 2021Article
- Type B lactic acidosis: a rare oncological emergency.BMJ case reports · 2020Article
- Impact of Sirtuin Enzymes on the Altered Metabolic Phenotype of Malignantly Transformed Cells.Frontiers in oncology · 2020Review
- Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells.Frontiers in oncology · 2020Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Major strides have been made in improving the treatment of medical emergencies associated with malignancies. Nonetheless, metabolic emergencies in cancer patients can often times be life-threatening. Type B lactic acidosis is a rare but potentially fatal paraneoplastic phenomenon that has been described in association with hematologic and solid malignancies and portends a poor prognosis if not rapidly recognized and treated. It is believed that this occurs as a result of cancer cells switching their glucose metabolism from an oxidative oxygen- dependent pathway towards a glycolytic phenotype, also known as the "Warburg effect". Though rare, it is important to consider this entity in the differential diagnosis of type B lactic acidosis since prompt identification and treatment may help improve outcomes in this otherwise fatal process. We present a case of type B lactic acidosis in a patient with chronic lymphocytic leukemia along with a brief review of the literature.
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26171281PMC4497494What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.