Evidence map›Paper›PMID 26171243›Full record

ArticleJournal of ophthalmology2015

Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study.

Dimitris Papaconstantinou, Andreas Diagourtas, Petros Petrou, Alexandros Rouvas, Athanasios Vergados, Chryssanthi Koutsandrea, Ilias Georgalas

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dimitris PapaconstantinouDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
Andreas DiagourtasDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
Petros PetrouDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
Alexandros RouvasDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
Athanasios VergadosDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
Chryssanthi KoutsandreaDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
Ilias GeorgalasDepartment of Ophthalmology, "G. Gennimatas" Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose. To compare the outcomes of trabeculectomy with and without Healaflow (Anteis S.A, Geneva, Switzerland), a high molecular weight viscoelastic gel, in patients requiring glaucoma surgery. Methods. This was a retrospective, comparative, interventional case-control study. Forty patients formed two matched study groups and were analyzed (trabeculectomy alone (control) versus trabeculectomy with Healaflow (study)). Results. The postoperative levels of mean IOP were statistically significantly lower (P < 0.05) than preoperatively in both groups, for all time intervals. There was no statistical difference, at the end of the follow-up period, between the two groups in the mean values of the IOP (14.9 ± 3.2 mmHg for the study group versus 14.8 ± 3.3 mmHg for the control group). The number of antiglaucoma drugs used in the study group was reduced from a preoperative mean of 3.4 ± 0.75 to a 6-month postoperative mean of 0.6 ± 0.8 (P < 0.001) and in the control group from 3.6 ± 0.59 to 0.55 ± 0.9 (P < 0.001). Conclusions. Although trabeculectomy with Healaflow appears to be a safe procedure, we failed to identify any significant advantages in the use of Healaflow when compared with trabeculectomy alone, at the end of the 6-month follow-up period.

Identifiers

PMID26171243
PMCPMC4480810
OpenAlexW1487765109

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.