ArticleOncology letters2015
Primary epithelial-myoepithelial carcinoma of the lung: A case report demonstrating high-grade transformation-like changes.
Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Epithelial-myoepithelial carcinoma of the lung: a case report and literature review.Journal of cancer research and clinical oncology · 2026Review
- Primary endobronchial epithelial-myoepithelial carcinoma: A case report and literature review.Experimental and therapeutic medicine · 2025Article
- Epithelial-myoepithelial carcinoma of the nasopharynx: A case report and review of the literature.Frontiers in oncology · 2022Article
- Pulmonary Epithelial-Myoepithelial Carcinoma.Journal of oncology · 2022Review
- Pulmonary epithelial-myoepithelial carcinoma without AKT1, HRAS or PIK3CA mutations: a case report.Diagnostic pathology · 2020Article
- [A Rare Case of Pulmonary Epithelial-myoepithelial Carcinoma: Case Report and Literature Review].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020Article
- Epithelial-myoepithelial carcinoma of the lung: a case report.Surgical case reports · 2018Article
- A rare case of primary peripheral epithelial myoepithelial carcinoma of lung: Case report and literature review.Medicine · 2016Review
- Pulmonary epithelial-myoepithelial carcinoma with high-grade transformation in a cat.JFMS open reportsArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary salivary gland-type tumors of the lung are rare; among them, epithelial-myoepithelial carcinomas (EMC) represent a minor histological subtype. The present case documents an EMC that occluded the B8 segment of the left lung in a 72-year-old woman. Macroscopically, the tumor was well-demarcated; however, microscopic examination demonstrated that it had infiltrated the lung parenchyma. The majority of the tumor mass was composed of a myoepithelial overgrowth in conjunction with conventional bilayered ductal structures comprising epithelial and myoepithelial cells. At the advancing edge of the tumor, the myoepithelial overgrowth was observed to be gradually transitioning to a higher-grade component, which demonstrated venous invasion. The Ki-67 labeling index was reduced compared with high-grade transformation (HGT) of salivary gland EMC; p53 was sparsely observed on immunostaining. However, cyclin D1, which is reported to be overexpressed in certain subtypes of salivary gland carcinomas with HGT, was overexpressed in the higher-grade component of the tumor, indicating a potential HGT initiation. The surgical margin was tumor free, and no recurrence has been observed for 4 months. A thorough follow-up is required considering the HGT-like changes and venous invasion of the tumor. Additional studies are required to elucidate the characteristics of pulmonary EMC, with an emphasis on detecting HGT or HGT-like changes.
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