Evidence map›Paper›PMID 26170969›Full record

ArticleOncology letters2015

Role of microRNA-150 in solid tumors.

Fang Wang, Xiubao Ren, Xinwei Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Effect of Whole-Brain and Intensity-Modulated Radiotherapy on Serum Levels of miR-21 and Prognosis for Lung Cancer Metastatic to the Brain.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Trial
  3. Article
  4. Review
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  6. Review
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  8. Review
  9. Article
  10. Article
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  12. G-Quadruplexes Regulate miRNA Biogenesis in Live Zebrafish Embryos.International journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fang WangDepartment of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, P.R. China ; National Clinical Research Center of Cancer, Tianjin 300060, P.R. China ; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, P.R. China.
Xiubao RenDepartment of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, P.R. China ; National Clinical Research Center of Cancer, Tianjin 300060, P.R. China ; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, P.R. China.
Xinwei ZhangDepartment of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, P.R. China ; National Clinical Research Center of Cancer, Tianjin 300060, P.R. China ; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, P.R. China.
Tianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a family of small endogenous noncoding RNAs and their altered expression has been associated with various cellular functions, including cell development, proliferation, differentiation, apoptosis, signal transduction, tumorigenesis and cancer progression. Accumulating evidence has indicated that miRNA (miR)-150 plays an essential regulatory role in normal hematopoiesis and tumorigenesis; therefore, miR-150 may be a potential biomarker and therapeutic target in the diagnosis and treatment of various malignancies. The aim of the present review was to summarize the current knowledge on the functions and regulatory mechanism of miR-150 as an oncogene or tumor suppressor gene in solid tumors. In addition, its potential application as a tumor biomarker, targeted therapeutic strategy and index of prognosis in various cancer types was investigated.

Indexed as

anti-oncogenemicroRNA-150oncogenesolid cancer

Identifiers

PMID26170969
PMCPMC4486901
OpenAlexW2134528950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.