Evidence map›Paper›PMID 26170948›Full record

ArticleExperimental and therapeutic medicine2015

Correlation of high-sensitivity C-reactive protein and carotid plaques with coronary artery disease in elderly patients.

Yanhong Liang, Yuanping Hou, Hongyu Niu, Mei Lu, Lei Xue, Qianmei Sun

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Evaluation of local carotid stiffness and inflammatory biomarkers in stable angina pectoris.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanhong LiangDepartment of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.
Yuanping HouDepartment of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.
Hongyu NiuDepartment of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.
Mei LuDepartment of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.
Lei XueDepartment of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.
Qianmei SunDepartment of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to explore the correlation of high-sensitivity C-reactive protein (hs-CRP) and carotid plaques with the severity of coronary artery disease (CAD). A total of 140 patients with angina who underwent coronary angiography were selected and divided into a single-vessel disease group (n=11), double-vessel disease group (n=18), multi-vessel disease group (n=71) and control group (n=40). Color Doppler ultrasound was applied to measure the intima-media thickness (IMT) of the common carotid artery (CCA) and carotid bifurcation, and to record the location and number of carotid plaques. The serum hs-CRP level was also determined. Compared with the control and single-vessel disease groups, the multi-vessel disease group showed significantly higher IMT of the CCA (P<0.05). The serum hs-CRP level was highest in the multi-vessel disease group (P<0.01). The hs-CRP level and carotid plaque characteristics were found to correlate closely with the severity of CAD. Therefore, they may be used to improve the prediction of CAD severity in elderly patients.

Indexed as

carotid plaquecoronary artery diseaseelderly patientshigh-sensitivity C-reactive protein

Identifiers

PMID26170948
PMCPMC4486787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.