ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2015
The pattern of early corneal endothelial cell recovery following cataract surgery: cellular migration or enlargement?
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Comparative analysis of endothelial cell loss following phacoemulsification in pupils of different sizes.Indian journal of ophthalmology · 2017Trial
- Comparative Analysis of Corneal Endothelial Cell Loss After Phacoemulsification in Microcornea versus Normal-Sized Corneas.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Correlation between early corneal edema and endothelial cell loss after phacoemulsification cataract surgery.Frontiers in medicine · 2025Article
- Clinical observation of phacoemulsification under the low perfusion pattern and low negative pressure in patients with low corneal endothelial cell density.BMC ophthalmology · 2023Article
- Commentary: Impact of intraocular surgeries on corneal endothelial cells in patients with diabetes mellitus.Indian journal of ophthalmology · 2022Article
- Short-Term Efficacy and Safety of Cataract Surgery Combined with Iris-Fixated Phakic Intraocular Lens Explantation: A Multicentre Study.Journal of clinical medicine · 2021Article
- Clinical course of lens capsule fragment adherent to the posterior corneal surface after cataract surgery.International ophthalmology · 2021Article
- Changes in the Density of Corneal Endothelial Cells in Elderly Diabetic Patients After Combined Phacovitrectomy and Ex-PRESS Glaucoma Implants.Current pharmaceutical biotechnology · 2019Article
- Effect of Cataract Surgery on the Refractive Index of the Cornea Estimated by Optical Pachymetry.Cornea · 2018Observational
- Corneal integrity and thickness of central fovea after phacoemulsification surgery in diabetic and nondiabetic cataract patients.Archives of medical science : AMS · 2018Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate whether cellular migration or enlargement is the main mechanism of initial endothelial cell recovery following cataract surgery.
methodsA prospective observational study, of 24 patients aged 50-80 years who were diagnosed with moderate cataract and received uncomplicated cataract surgery with a 2.75 mm temporal clear corneal incision, was performed in Seoul National University Bundang Hospital. Endothelial cell density (ECD) and area (ECA) were obtained in central and four paracentral (superior, inferior, nasal, and temporal) areas using non-contact specular microscopy. ECD, ECA, ECD% (ECD% = ECD in each area/the sum total of ECD in five areas), and the coefficient of variation of ECA (CV) in each location were investigated pre- and 1 day, 1 week, and 4 weeks postoperatively.
resultsECD significantly decreased 1 day, 1 week, and 4 weeks postoperatively (p = 0.010, 0.015, and 0.003 respectively), and ECA increased (p = 0.008, 0.013, and 0.002 respectively) in only the temporal area. Postoperative ECD% decreased, and CV increased in only the temporal area significantly, when compared to preoperative values. There were no significant postoperative changes of ECD, ECA, ECD%, and CV in other areas.
conclusionsPostoperative changes of ECD, ECA, ECD%, and CV were limited to the temporal area adjacent to the primary corneal incision. Cellular enlargement, rather than migration, may have the major effect on early endothelial cell recovery after cataract surgery.
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