ArticleBMJ open2015
Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA).
Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Prescription of Lipid-Lowering and Antihypertensive Drugs Following Pictorial Information About Subclinical Atherosclerosis: A Secondary Outcome of a Randomized Clinical Trial.JAMA network open · 2021Trial
- Statin Use is Not Associated with Future Long-Term Care Admission: Extended Follow-Up of Two Randomised Controlled Trials.Drugs & aging · 2018Trial
- Goal attainment, medication adherence and guideline adherence in the treatment of hypertension and dyslipidemia in Irish populations: A systematic review and meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2025Review
- ASPC president's page: Getting back to basics one patient at a time.American journal of preventive cardiology · 2022Article
- Machine learning approaches improve risk stratification for secondary cardiovascular disease prevention in multiethnic patients.Open heart · 2021Article
- A Novel Statin Compound from Monacolin J Produced Using CYP102A1-Catalyzed Regioselective C-Hydroxylation.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Understanding providers' attitudes and key concerns toward incorporating CVD risk prediction into clinical practice: a qualitative study.BMC health services research · 2021Article
- A snapshot of lipid levels in the Republic of Ireland in 2017.Irish journal of medical science · 2019Article
- Article
- Suboptimal lipid management before and after ischaemic stroke and TIA-the North Dublin Population Stroke Study.Irish journal of medical science · 2018Article
- Article
- Associations of statin use with motor performance and myalgia may be modified by 25-hydroxyvitamin D: findings from a British birth cohort.Scientific reports · 2017Article
- Explanation and elaboration of the SQUIRE (Standards for Quality Improvement Reporting Excellence) Guidelines, V.2.0: examples of SQUIRE elements in the healthcare improvement literature.BMJ quality & safety · 2016Article
- Statins are underused in recent-onset Parkinson's disease with increased vascular risk: findings from the UK Tracking Parkinson's and Oxford Parkinson's Disease Centre (OPDC) discovery cohorts.Journal of neurology, neurosurgery, and psychiatry · 2016Article
- Low use of statins for secondary prevention in primary care: a survey in a northern Swedish population.BMC family practice · 2016Article
- Do newly marketed generic medicines expand markets using descriptive time series analysis and mixed logit models? Korea as an exemplar and its implications.BMC health services research · 2016Article
- Time trends in statin utilisation and coronary mortality in Western European countries.BMJ open · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) known CVD, (2) known diabetes and (3) a high or very high risk (≥5%) of CVD mortality based on Systematic COronary Risk Evaluation (SCORE).
designThis study is cross-sectional in design using data from the first wave (2009-2011) of The Irish Longitudinal Study on Ageing (TILDA). SETTING AND
participantsThe sample (n=3372) is representative of community living adults aged 50-64 years in Ireland.
resultsStatins were used by 68.6% (95% CI 61.5% to 75.8%) of those with known CVD, 57.4% (95% CI 49.1% to 65.7%) of those with known diabetes and by 19.7% (95% CI 13.0% to 26.3%) of adults with a SCORE risk ≥5%. Over a third (38.5%, 95% CI 31.0% to 46.0%) of those with known CVD, 46.8% (95% CI 38.4% to 55.1%) of those with known diabetes and 85.2% (95% CI 79.3% to 91.1%) of those with a SCORE risk ≥5% were at or above the low-density lipoprotein cholesterol (LDL-C) target of 2.5 mmol/L specified in the 2007 European guidelines.
conclusionsDespite strong evidence and clinical guidelines recommending the use of statins for secondary prevention, a gap exists between guidelines and practice in this cohort. It is also of concern that a low proportion of adults with a SCORE risk ≥5% were taking statins. A policy response that strengthens secondary prevention, and improves risk assessment and shared decision-making in the primary prevention of CVD is required.
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