Evidence map›Paper›PMID 26169534›Full record

ArticleJournal of the American Heart Association2015

New York State: Comparison of Treatment Outcomes for Unruptured Cerebral Aneurysms Using an Instrumental Variable Analysis.

Kimon Bekelis, Symeon Missios, Shannon Coy, Robert J Singer, Todd A MacKenzie

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  6. Review
  7. Article
  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kimon BekelisSection of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH (K.B., R.J.S.).
Symeon MissiosDepartment of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA (S.M.).
Shannon CoyGeisel School of Medicine at Dartmouth, Hanover, NH (S.C.).
Robert J SingerSection of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH (K.B., R.J.S.).
Todd A MacKenzieDepartment of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH (T.A.M.K.) Department of Community and Family Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH (T.A.M.K.) The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (T.A.M.K.).
Dartmouth–Hitchcock Medical Center · USDartmouth College · USLouisiana State University Health Sciences Center Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is wide regional variation in the predominant treatment for unruptured cerebral aneurysms. We investigated the association of elective surgical clipping and endovascular coiling with mortality, readmission rate, length of stay, and discharge to rehabilitation. METHODS AND

resultsWe performed a cohort study involving patients with unruptured cerebral aneurysms, who underwent surgical clipping or endovascular coiling from 2009 to 2013 and were registered in the Statewide Planning and Research Cooperative System database. An instrumental variable analysis was used to investigate the association of treatment technique with outcomes. Of the 4643 patients undergoing treatment, 3190 (68.7%) underwent coiling, and 1453 (31.3%) underwent clipping. Using an instrumental variable analysis, we did not identify a difference in inpatient mortality (marginal effect, 0.13; 95% CI, -0.30, 0.57), or the rate of 30-day readmission (marginal effect, -1.84; 95% CI -4.06, -0.37) between the 2 treatment techniques for patients with unruptured cerebral aneurysms. Clipping was associated with a higher rate of discharge to rehabilitation (marginal effect, 2.31; 95% CI 0.21, 4.41), and longer length of stay (β, 2.01; 95% CI 0.85, 3.04). In sensitivity analysis, mixed-effect regression, and propensity score, adjusted regression models demonstrated identical results.

conclusionsUsing a comprehensive all-payer cohort of patients in New York State with unruptured cerebral aneurysms, we did not identify an association of treatment method with mortality or 30-day readmission. Clipping was associated with a higher rate of discharge to rehabilitation and longer length of stay.

Indexed as

Data MiningEndovascular ProceduresVascular Surgical ProceduresAdultAgedDatabases, FactualFemaleHospital MortalityHumansIntracranial AneurysmLength of StayLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate Analysisclippingcoilinginstrumental variablestatewide planning and research cooperative systemunruptured cerebral aneurysm

Identifiers

PMID26169534
PMCPMC4608094
OpenAlexW2169542339

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.