Evidence map›Paper›PMID 26169322›Full record

ArticleNeuroImage2015

Rapid 3D dynamic arterial spin labeling with a sparse model-based image reconstruction.

Li Zhao, Samuel W Fielden, Xue Feng, Max Wintermark, John P Mugler, Craig H Meyer

Abstract read
In one paragraph

Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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  13. HyperpolarizedDiagnostics (Basel, Switzerland) · 2020
    Article
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  17. Controlling TMagnetic resonance in medicine · 2018
    Article
  18. Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018
    Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Li ZhaoDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Samuel W FieldenDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Xue FengDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Max WintermarkDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
John P MuglerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA; Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA.
Craig H MeyerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA; Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA. Electronic address: cmeyer@virginia.edu.
University of Virginia · US

Funding

Improved MR Techniques for Coronary Artery ImagingR01HL079110 · NHLBI · UNIVERSITY OF VIRGINIA · PI MEYER, CRAIG H · 2006 to 2010
$1.8M
NHLBI NIH HHS R01 HL079110
6 · The paper itself

Abstract

Dynamic arterial spin labeling (ASL) MRI measures the perfusion bolus at multiple observation times and yields accurate estimates of cerebral blood flow in the presence of variations in arterial transit time. ASL has intrinsically low signal-to-noise ratio (SNR) and is sensitive to motion, so that extensive signal averaging is typically required, leading to long scan times for dynamic ASL. The goal of this study was to develop an accelerated dynamic ASL method with improved SNR and robustness to motion using a model-based image reconstruction that exploits the inherent sparsity of dynamic ASL data. The first component of this method is a single-shot 3D turbo spin echo spiral pulse sequence accelerated using a combination of parallel imaging and compressed sensing. This pulse sequence was then incorporated into a dynamic pseudo continuous ASL acquisition acquired at multiple observation times, and the resulting images were jointly reconstructed enforcing a model of potential perfusion time courses. Performance of the technique was verified using a numerical phantom and it was validated on normal volunteers on a 3-Tesla scanner. In simulation, a spatial sparsity constraint improved SNR and reduced estimation errors. Combined with a model-based sparsity constraint, the proposed method further improved SNR, reduced estimation error and suppressed motion artifacts. Experimentally, the proposed method resulted in significant improvements, with scan times as short as 20s per time point. These results suggest that the model-based image reconstruction enables rapid dynamic ASL with improved accuracy and robustness.

Indexed as

AdultCerebrovascular CirculationHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographySpin LabelsSpin LabelsArterial spin labelingBrain perfusion MRICompressed sensingDynamic ASLModel-based sparsitySingle-shot spiral ASL

Identifiers

PMID26169322
PMCPMC4615585
OpenAlexW752475946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.