ArticleAnalytical and bioanalytical chemistry2015
Recent advances in quantitative LA-ICP-MS analysis: challenges and solutions in the life sciences and environmental chemistry.
Article in Analytical and bioanalytical chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- A novel approach for monitoring the spatial distribution and quantitative analysis of micronutrients in plant tissues using laser ablation ICP-MS imaging.Analytical and bioanalytical chemistry · 2026Article
- Quantitative LA-ICP-MS Imaging of Elemental Distributions with Protein Correlation in 3D Tumor Models.Analytical chemistry · 2026Article
- USPIO enhanced MR imaging in CNS tumors (UMIC): a study protocol.Nanomedicine (London, England) · 2026Article
- Wavelength Dependence of fs Laser Ablation Ionisation Mass Spectrometry: a Dedicated Study on NIST SRM 664.Rapid communications in mass spectrometry : RCM · 2026Article
- On-slide Preparation ofbioRxiv : the preprint server for biology · 2026Article
- Nanoparticle Detection in Biology and Medicine: A Review.Biosensors · 2025Review
- Cadmium toxicity in plants: from transport to tolerance mechanisms.Plant signaling & behavior · 2025Review
- Quantitative analysis using LA-ICP-MS and powder samples dispersed in polyvinyl alcohol films.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- LA-ICP-TOF-MS for quantitative mapping of biogenic carbonate samples using matrix-matched nanoparticulate pressed powder pellets.Journal of analytical atomic spectrometry · 2025Article
- Investigating metal distribution patterns in pristine and ocean-weathered plastics using LA-ICP-TOFMS.Journal of analytical atomic spectrometry · 2025Article
- Human hair as a diagnostic tool in medicine.Biochemistry and biophysics reports · 2025Review
- Mass Spectrometry Imaging.Analytical chemistry · 2025Review
- A Method for Determination of Transport Efficiency in Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Tissue Analysis.Analytical chemistry · 2025Article
- A Laser Ablation ICP-MS Protocol for High-Resolution Iodine-to-Calcium Ratio (I/Ca) Analysis on Corals.Rapid communications in mass spectrometry : RCM · 2025Article
- Ways to Measure Metals: From ICP-MS to XRF.Current environmental health reports · 2025Review
- Mapping elemental solutes at sub-picogram levels during aqueous corrosion of Al alloys using diffusive gradients in thin films (DGT) with LA-ICP-MS.Analytical and bioanalytical chemistry · 2024Article
- Feasibility of Matrix-Matched Material for Determining Elements in Rice Flour by SN-ICP-MS and LA-ICP-MS.Foods (Basel, Switzerland) · 2024Article
- One-point calibration and matrix-matching concept for quantification of potentially toxic elements in wood by LA-ICP-MS.Analytical and bioanalytical chemistry · 2024Article
- Article
- In Vitro Fossilization for High Spatial Resolution Quantification of Elements in Plant-Tissue Using LA-ICP-TOFMS.Analytical chemistry · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) is a widely accepted method for direct sampling of solid materials for trace elemental analysis. The number of reported applications is high and the application range is broad; besides geochemistry, LA-ICP-MS is mostly used in environmental chemistry and the life sciences. This review focuses on the application of LA-ICP-MS for quantification of trace elements in environmental, biological, and medical samples. The fundamental problems of LA-ICP-MS, such as sample-dependent ablation behavior and elemental fractionation, can be even more pronounced in environmental and life science applications as a result of the large variety of sample types and conditions. Besides variations in composition, the range of available sample states is highly diverse, including powders (e.g., soil samples, fly ash), hard tissues (e.g., bones, teeth), soft tissues (e.g., plants, tissue thin-cuts), or liquid samples (e.g., whole blood). Within this article, quantification approaches that have been proposed in the past are critically discussed and compared regarding the results obtained in the applications described. Although a large variety of sample types is discussed within this article, the quantification approaches used are similar for many analytical questions and have only been adapted to the specific questions. Nevertheless, none of them has proven to be a universally applicable method.
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Registered trials
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