Evidence map›Paper›PMID 26168922›Full record

ArticleHealth and quality of life outcomes2015

Mobility predicts change in older adults' health-related quality of life: evidence from a Vancouver falls prevention prospective cohort study.

Jennifer C Davis, Stirling Bryan, John R Best, Linda C Li, Chun Liang Hsu, Caitlin Gomez, Kelly A Vertes, Teresa Liu-Ambrose

Abstract read
In one paragraph

Article in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  9. Sensorimotor correlates of sit-to-stand in healthy adults.Frontiers in bioengineering and biotechnology · 2025
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  14. Do physical fitness and cognitive function mediate the relationship between basic activities of daily living and quality of life in older adults with dementia?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer C DavisCentre for Clinical Epidemiology and Evaluation, University of British Columbia and Vancouver Coastal Health Research Institute (VCHRI), 828 West 10th Avenue, Vancouver, BC, V6T 2B5, Canada. jennifer.davis@ubc.ca.
Stirling BryanCentre for Clinical Epidemiology and Evaluation, University of British Columbia and Vancouver Coastal Health Research Institute (VCHRI), 828 West 10th Avenue, Vancouver, BC, V6T 2B5, Canada. Stirling.Bryan@ubc.ca.
John R BestDepartment of Physical Therapy, University of British Columbia, 2177 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. john.best@ubc.ca.
Linda C LiDepartment of Physical Therapy, University of British Columbia, 2177 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. lli@arthritisresearch.ca.
Chun Liang HsuDepartment of Physical Therapy, University of British Columbia, 2177 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. liang.hsu@hiphealth.ca.
Caitlin GomezAging, Mobility, and Cognitive Neuroscience Lab, University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. caitlin.gomez@hiphealth.ca.
Kelly A VertesAging, Mobility, and Cognitive Neuroscience Lab, University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. kelly.vertes@hiphealth.ca.
Teresa Liu-AmbroseDepartment of Physical Therapy, University of British Columbia, 2177 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. teresa.ambrose@ubc.ca.

Funding

Chief Scientist Office HERU1CIHR MOB-93373
6 · The paper itself

Abstract

backgroundOlder adults with mobility impairments are prone to reduced health related quality of life (HRQoL) is highly associated with mobility impairments. The consequences of falls have detrimental impact on mobility. Hence, ascertaining factors explaining variation among individuals' quality of life is critical for promoting healthy ageing, particularly among older fallers. Hence, the primary objective of our study was to identify key factors that explain variation in HRQoL among community dwelling older adults at risk of falls.

methodsWe conducted a longitudinal analysis of a 12-month prospective cohort study at the Vancouver Falls Prevention Clinic (n = 148 to 286 depending on the analysis). We constructed linear mixed models where assessment month (0, 6, 12) was entered as a within-subjects repeated measure, the intercept was specified as a random effect, and predictors and covariates were entered as between-subjects fixed effects. We also included the predictors by sex and predictor by sex by time interaction terms in order to investigate sex differences in the relations between the predictor variable and the outcome variable, the EQ-5D.

resultsOur primary analysis demonstrated a significant mobility (assessed using the Short Performance Physical Battery and the Timed Up and Go) by time interaction (p < 0.05) and mobility by time by sex interaction (p < 0.05). The sensitivity analyses demonstrated some heterogeneity of these findings using an imputed and a complete case analysis.

conclusionsMobility may be an important predictor of changes in HRQoL over time. As such, mobility is a critical factor to target for future intervention strategies aimed at maintaining or improving HRQoL in late life.

Indexed as

Health StatusMobility LimitationQuality of LifeAccidental FallsAgedAged, 80 and overBritish ColumbiaCohort StudiesFemaleGeriatric AssessmentHumansMaleProspective StudiesResidence Characteristics

Identifiers

PMID26168922
PMCPMC4501103

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.