ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2016
Application of the F-Response for Estimating Motor Unit Number and Amplitude Distribution in Hand Muscles of Stroke Survivors.
Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Structural and pathophysiological muscle changes up to one year after post-stroke hemiplegia: a systematic review.European journal of physical and rehabilitation medicine · 2023Pooled it
- Characterizing repeater F waves using the compound muscle action potential scan and machine learning techniques.Neurophysiologie clinique = Clinical neurophysiology · 2025Article
- Using mechanistic knowledge to appraise contemporary approaches to the rehabilitation of upper limb function following stroke.The Journal of physiology · 2025Review
- F wave analysis based on the compound muscle action potential scan.Muscle & nerve · 2024Article
- Article
- The relationship between the functional status of upper extremity motor neurons and motor function and prognosis in stroke patients.Frontiers in neurology · 2024Article
- Compound muscle action potential (CMAP) scan examination of paretic and contralateral muscles reveals motor unit alterations after stroke.Science China. Life sciences · 2023Article
- Fully automated F-wave corridor extraction and analysis algorithm for F-wave analyses and MUNE studies.Scientific reports · 2023Article
- Motor Unit Number Estimation in Spastic Biceps Brachii Muscles of Chronic Stroke Survivors Before and After BoNT Injection.IEEE transactions on bio-medical engineering · 2023Article
- Electrical impedance myography combined with quantitative assessment techniques in paretic muscle of stroke survivors: Insights and challenges.Frontiers in aging neuroscience · 2023Article
- Motor Unit Number Estimation (MUNE) Free of Electrical Stimulation or M Wave Recording: Feasibility and Challenges.Frontiers in aging neuroscience · 2022Article
- Ischemic stroke-induced polyaxonal innervation at the neuromuscular junction is attenuated by robot-assisted mechanical therapy.Experimental neurology · 2021Article
- How Does Stroke Affect Skeletal Muscle? State of the Art and Rehabilitation Perspective.Frontiers in neurology · 2021Review
- Muscle Fiber Diameter and Density Alterations after Stroke Examined by Single-Fiber EMG.Neural plasticity · 2021Article
- Model-Based Analysis of Muscle Strength and EMG-Force Relation with respect to Different Patterns of Motor Unit Loss.Neural plasticity · 2021Article
- Brain and Muscle: How Central Nervous System Disorders Can Modify the Skeletal Muscle.Diagnostics (Basel, Switzerland) · 2020Review
- Assessing Hand Muscle Structural Modifications in Chronic Stroke.Frontiers in neurology · 2018Article
- Motor Unit Properties of the First Dorsal Interosseous in Chronic Stroke Subjects: Concentric Needle and Single Fiber EMG Analysis.Frontiers in physiology · 2018Article
- Electrical Impedance Myography for Evaluating Paretic Muscle Changes After Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2017Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
The F-response was used in this study to assess changes in the first dorsal interosseous (FDI) muscle after a hemispheric stroke. The number of motor units and their sizes were estimated bilaterally in 12 stroke survivors by recording both the compound muscle action potential (CMAP) and F wave responses. These F waves were induced by applying a large number of electrical stimuli to the ulnar nerve. The amplitude distribution of individual motor unit action potentials (MUAPs) was also compared between paretic and contralateral muscles. When averaged across all the subjects, a significantly lower motor unit number estimate was obtained for the paretic FDI muscle ( 88 ±13) compared with the contralateral side ( 139 ±11) ( ). Pooled surface MUAP amplitude analysis demonstrated a right-skewed distribution for both paretic (kurtosis 3.0) and contralateral (kurtosis 8.52) muscles. When normalized to each individual muscle's CMAP, the surface MUAP amplitude ranged from 0.22% to 4.94% (median 1.17%) of CMAP amplitude for the paretic muscle, and from 0.13% to 3.2% (median 0.62%) of CMAP amplitude for the contralateral muscle. A significant difference in MUAP outliers was also observed between the paretic and contralateral muscles. The findings of this study suggest significant motor unit loss and muscle structural reorganization after stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.