Evidence map›Paper›PMID 26167510›Full record

ArticleBioMed research international2015

Relationship between Outer Retinal Layers Thickness and Visual Acuity in Diabetic Macular Edema.

Raymond L M Wong, Jacky W Y Lee, Gordon S K Yau, Ian Y H Wong

Abstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Diabetic macular edema: Evidence-based management.Indian journal of ophthalmology · 2018
    Review
  10. Article
  11. En face Integrated Central Avascular Zone (EFICAZ): a noninvasive tool for correlating morphological and functional damage in central diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017
    Article
  12. Correlation between outer retinal layer thickness and cone density in patients with resolved central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raymond L M WongDepartment of Ophthalmology, The University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, Pokfulam, Hong Kong ; Department of Ophthalmology and Visual Science, The Chinese University of Hong Kong, Kowloon, Hong Kong.
Jacky W Y LeeDepartment of Ophthalmology, The University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, Pokfulam, Hong Kong ; Department of Ophthalmology, Caritas Medical Centre, Kowloon, Hong Kong.
Gordon S K YauDepartment of Ophthalmology, Caritas Medical Centre, Kowloon, Hong Kong.
Ian Y H WongDepartment of Ophthalmology, The University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, Pokfulam, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the correlation of outer retinal layers (ORL) thickness and visual acuity (VA) in patients with diabetic macular edema (DME).

methodsConsecutive DME patients seen at the Retina Clinic of The University of Hong Kong were recruited for OCT assessment. The ORL thickness was defined as the distance between external limiting membrane (ELM) and retinal pigment epithelium (RPE) at the foveal center. The correlation between total retinal thickness, ORL thickness, and vision was calculated.

results78 patients with DME were recruited. The mean age was 58.1 years (±11.5 years) and their mean visual acuity measured with Snellen chart was 0.51 (±0.18). The correlation coefficient between total retinal thickness and visual acuity was 0.34 (P < 0.001) whereas the correlation coefficient was 0.65 between ORL thickness and visual acuity (P < 0.001).

conclusionORL thickness correlates better with vision than the total retinal thickness. It is a novel OCT parameter in the assessment of DME. Moreover, it could be a potential long term visual prognostic factor for patients with DME.

Indexed as

Diabetic RetinopathyMacular EdemaAgedCohort StudiesFemaleHumansMaleMiddle AgedRetinaTomography, Optical CoherenceVisual Acuity

Identifiers

PMID26167510
PMCPMC4475736

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