Evidence map›Paper›PMID 26167481›Full record

ArticleBioMed research international2015

Accelerated Recovery of Endothelium Function after Stent Implantation with the Use of a Novel Systemic Nanoparticle Curcumin.

Qi Lu, Fang Ye, Xiangjun Yang, Qingqing Gu, Peng Wang, Jianhua Zhu, Li Shen, Feirong Gong

Abstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. An Integrated Arterial Remodeling Hydrogel for Preventing Restenosis After Angioplasty.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qi LuDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong 226001, China.
Fang YeDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Xiangjun YangDepartment of Cardiology, First Affiliated People's Hospital of Suzhou University, Suzhou 215006, China.
Qingqing GuDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong 226001, China.
Peng WangDepartment of Electrocardiogram, First Affiliated People's Hospital of Suzhou University, Suzhou 215006, China.
Jianhua ZhuDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong 226001, China.
Li ShenDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Feirong GongKey Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin was reported to exhibit a wide range of pharmacological effects including antioxidant, anti-inflammatory, and antiproliferative activities and significantly prevent smooth muscle cells migration. In the present study, a novel kind of curcumin loaded nanoparticles (Cur-NP) has been prepared and characterized with the aim of inhibiting inflammation formation and accelerating the healing process of the stented arteries. Cur-NP was administrated intravenously after stent implantation twice a week and detailed tissue responses were evaluated. The results demonstrated that intravenous administration of Cur-NP after stent implantation accelerated endothelial cells restoration and endothelium function recovery and may potentially be an effective therapeutic alternative to reduce adverse events for currently available drug eluting stents.

Indexed as

Drug-Eluting StentsAnimalsAnti-Inflammatory AgentsAortaCells, CulturedCell SurvivalCurcuminDrug StabilityEndothelium, VascularMaleRatsSwineAnti-Inflammatory AgentsCurcumin

Identifiers

PMID26167481
PMCPMC4475764

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.