Evidence map›Paper›PMID 26167474›Full record

SynthesisBioMed research international2015

Advanced Morphological and Functional Magnetic Resonance Techniques in Glaucoma.

Rodolfo Mastropasqua, Luca Agnifili, Peter A Mattei, Massimo Caulo, Vincenzo Fasanella, Riccardo Navarra, Leonardo Mastropasqua, Giorgio Marchini

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. The Hub-and-Spoke Management of Glaucoma.Frontiers in neuroscience · 2020
    Review
  6. Review
  7. Article
  8. Effects of brinzolamide on rabbit ocular blood flowInternational journal of ophthalmology · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rodolfo MastropasquaOphthalmology Unit, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, 37121 Verona, Italy.
Luca AgnifiliOphthalmology Clinic, Department of Medicine and Aging Science, G. d'Annunzio University of Chieti-Pescara, 65100 Chieti, Italy.
Peter A MatteiOphthalmology Clinic, Department of Medicine and Aging Science, G. d'Annunzio University of Chieti-Pescara, 65100 Chieti, Italy.
Massimo CauloDepartment of Neuroscience and Imaging, G. d'Annunzio University of Chieti-Pescara, 65100 Chieti, Italy.
Vincenzo FasanellaOphthalmology Clinic, Department of Medicine and Aging Science, G. d'Annunzio University of Chieti-Pescara, 65100 Chieti, Italy.
Riccardo NavarraDepartment of Neuroscience and Imaging, G. d'Annunzio University of Chieti-Pescara, 65100 Chieti, Italy.
Leonardo MastropasquaOphthalmology Clinic, Department of Medicine and Aging Science, G. d'Annunzio University of Chieti-Pescara, 65100 Chieti, Italy.
Giorgio MarchiniOphthalmology Unit, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, 37121 Verona, Italy.
University of Chieti-Pescara · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is a multifactorial disease that is the leading cause of irreversible blindness. Recent data documented that glaucoma is not limited to the retinal ganglion cells but that it also extends to the posterior visual pathway. The diagnosis is based on the presence of signs of glaucomatous optic neuropathy and consistent functional visual field alterations. Unfortunately these functional alterations often become evident when a significant amount of the nerve fibers that compose the optic nerve has been irreversibly lost. Advanced morphological and functional magnetic resonance (MR) techniques (morphometry, diffusion tensor imaging, arterial spin labeling, and functional connectivity) may provide a means for observing modifications induced by this fiber loss, within the optic nerve and the visual cortex, in an earlier stage. The aim of this systematic review was to determine if the use of these advanced MR techniques could offer the possibility of diagnosing glaucoma at an earlier stage than that currently possible.

Indexed as

Diagnostic Techniques, OphthalmologicalGlaucomaHumansMagnetic Resonance Imaging

Identifiers

PMID26167474
PMCPMC4475765
OpenAlexW1489286691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.