ReviewWorld journal of nephrology2015
Estimating glomerular filtration rate in kidney transplantation: Still searching for the best marker.
Review in World journal of nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Reno-protective effects of perioperative dexmedetomidine in kidney transplantation: a systematic review and meta-analysis of randomized controlled trials.International urology and nephrology · 2023Pooled it
- First Experience with [Diagnostics (Basel, Switzerland) · 2026Article
- Porcine xenotransplantation in the clinical era: converging advances and unresolved barriers on the path to clinical translation - a narrative review.Frontiers in immunology · 2026Review
- Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction.World journal of transplantation · 2024Article
- Review
- Living donors kidney transplantation and oxidative stress: Nitric oxide as a predictive marker of graft function.PloS one · 2024Article
- Evaluating Dynamic Discrimination Performance of Risk Prediction Models for Survival Outcomes.Statistics in biosciences · 2023Article
- Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.BMJ (Clinical research ed.) · 2023Article
- Revisiting transplant immunology through the lens of single-cell technologies.Seminars in immunopathology · 2023Review
- Physiological aspects of pig kidney xenotransplantation and implications for management following transplant.Xenotransplantation · 2022Review
- Association of serum bicarbonate with graft survival and mortality in kidney transplant recipients.Journal of nephrology · 2022Article
- Allograft Function as Endpoint for Clinical Trials in Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
- Mathematical model for early functional recovery pattern of kidney transplant recipients using serum creatinine.Korean journal of transplantation · 2020Article
- Evaluation of Neutrophil Gelatinase-Associated Lipocalin and Cystatin C in Early Diagnosis of Chronic Kidney Disease in the Absence of the Gold Standard.Galen medical journal · 2020Article
- The efficacy of HBOC-201 in ex situ gradual rewarming kidney perfusion in a rat model.Artificial organs · 2020Article
- A retrospective study of the relationship between postoperative urine output and one year transplanted kidney function.BMC anesthesiology · 2019Article
- Using Post Transplant 1 Week Tc-99m DPTA Renal Scan as Another Method for Predicting Renal Graft Failure.Open medicine (Warsaw, Poland) · 2019Article
- Preservation of kidney function in kidney transplant recipients by alkali therapy (Preserve-Transplant Study): rationale and study protocol.BMC nephrology · 2018Article
- Assessing Glomerular Filtration in Small Animals Using [Molecular imaging and biology · 2018Article
- Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Allograft Function After Renal Transplantation: Evaluation of the Current Status and Future Insights.Artificial organs · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kidney transplantation is the treatment of choice for end-stage renal disease. The evaluation of graft function is mandatory in the management of renal transplant recipients. Glomerular filtration rate (GFR), is generally considered the best index of graft function and also a predictor of graft and patient survival. However GFR measurement using inulin clearance, the gold standard for its measurement and exogenous markers such as radiolabeled isotopes ((51)Cr EDTA, (99m)Tc DTPA or (125)I Iothalamate) and non-radioactive contrast agents (Iothalamate or Iohexol), is laborious as well as expensive, being rarely used in clinical practice. Therefore, endogenous markers, such as serum creatinine or cystatin C, are used to estimate kidney function, and equations using these markers adjusted to other variables, mainly demographic, are an attempt to improve accuracy in estimation of GFR (eGFR). Nevertheless, there is some concern about the inability of the available eGFR equations to accurately identify changes in GFR, in kidney transplant recipients. This article will review and discuss the performance and limitations of these endogenous markers and their equations as estimators of GFR in the kidney transplant recipients, and their ability in predicting significant clinical outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.